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ACTR1B 抗体 (C-Term)

Cited in 1 publication. This anti-ACTR1B antibody is a 兔 多克隆 antibody detecting ACTR1B in WB. Suitable for 人, 小鼠, 大鼠, 犬, 兔, Cow, 豚鼠, 马 和 斑马鱼.
产品编号 ABIN2784773
发货至: 中国
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Quick Overview for ACTR1B 抗体 (C-Term) (ABIN2784773)

抗原

See all ACTR1B 抗体
ACTR1B (ARP1 Actin-Related Protein 1 Homolog B, Centractin beta (ACTR1B))

适用

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人, 小鼠, 大鼠, 犬, 兔, Cow, 豚鼠, 马, 斑马鱼

宿主

  • 31
  • 2
  • 1

克隆类型

  • 24
  • 9
多克隆

标记

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This ACTR1B antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

    • 2
    • 1
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    • 1
    • 1
    C-Term

    序列

    KIKISAPQER LYSTWIGGSI LASLDTFKKM WVSKKEYEED GSRAIHRKTF

    预测反应

    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

    产品特性

    This is a rabbit polyclonal antibody against ACTR1B. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the C terminal region of human ACTR1B
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 376 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Hwang, Weng, Lin, Bau, Ko, Tsai, Tsai, Wu, Lin, Huang, Kuo: "Hypoxia-induced compensatory effect as related to Shh and HIF-1alpha in ischemia embryo rat heart." in: Molecular and cellular biochemistry, Vol. 311, Issue 1-2, pp. 179-87, (2008) (PubMed).

  • 抗原

    ACTR1B (ARP1 Actin-Related Protein 1 Homolog B, Centractin beta (ACTR1B))

    别名

    ACTR1B

    背景

    ACTR1B is a 42.3 kD subunit of dynactin, a macromolecular complex consisting of 10 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein and is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. ACTR1B, like ACTR1A, is an actin-related protein. These two proteins, which are of equal length and share 90 % amino acid identity, are present in a constant ratio of approximately 1:15 in the dynactin complex.This gene encodes a 42.3 kD subunit of dynactin, a macromolecular complex consisting of 10 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit, like ACTR1A, is an actin-related protein. These two proteins are of equal length and share 90 % amino acid identity. They are present in a constant ratio of approximately 1:15 in the dynactin complex.
    Alias Symbols: ARP1B, CTRN2, PC3
    Protein Interaction Partner: SEH1L, ACTR10, DCTN4, DCTN2, ACTR1A, RABEP1, LMNB1, DCTN3, APP, SMAD6, CUL3, UBC, TK1, MAPK6, CSNK2B, Dctn1, Capza1, CHD3, ACTA1,
    Protein Size: 376

    分子量

    42 kDa

    基因ID

    10120

    NCBI登录号

    NM_005735, NP_005726

    UniProt

    P42025
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