SAE1 抗体 (N-Term)
Quick Overview for SAE1 抗体 (N-Term) (ABIN2784764)
抗原
See all SAE1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- N-Term
-
序列
- VTPEDPGAQF LIRTGSVGRN RAEASLERAQ NLNPMVDVKV DTEDIEKKPE
-
预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 93%
-
产品特性
- This is a rabbit polyclonal antibody against SAE1. It was validated on Western Blot using a cell lysate as a positive control.
-
纯化方法
- Affinity Purified
-
免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human SAE1
-
-
-
-
应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
-
说明
-
Antigen size: 346 AA
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- Lot specific
-
缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freeze-thaw cycles.
-
储存条件
- -20 °C
-
储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
-
- SAE1 (SUMO1 Activating Enzyme Subunit 1 (SAE1))
-
别名
- SAE1
-
背景
-
Posttranslational modification of proteins by the addition of the small protein SUMO (see SUMO1, MIM 601912), or sumoylation, regulates protein structure and intracellular localization. SAE1 and UBA2 (MIM 613295) form a heterodimer that functions as a SUMO-activating enzyme for the sumoylation of proteins (Okuma et al., 1999 [PubMed 9920803]).
Alias Symbols: AOS1, FLJ3091, HSPC140, SUA1, UBLE1A
Protein Interaction Partner: FUS, USP39, SUMO2, HSPA2, HSPA1A, UBC, TRMT10A, DPP9, RPRD1B, NPLOC4, OSGEP, PANK4, WDR4, CUL5, TPD52L2, SRP14, RANGAP1, PPP2R5E, MCM3, LPP, DHPS, CALU, ADSL, AARS, PDE12, TP53RK, UBE2I, UBA2, BAG3, PTK2, IL3RA, APP, SUMO1, ETV4, BCL6, UBE2E3, SUMO3, SP10
Protein Size: 346 -
分子量
- 38 kDa
-
基因ID
- 10055
-
NCBI登录号
- NM_005500, NP_005491
-
UniProt
- Q9UBE0
抗原
-