CRYBA1 抗体 (N-Term)
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北京 101111
Quick Overview for CRYBA1 抗体 (N-Term) (ABIN2784755)
抗原
See all CRYBA1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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原理
- CRYBA1 Antibody - N-terminal region
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序列
- METQAEQQEL ETLPTTKMAQ TNPTPGSLGP WKITIYDQEN FQGKRMEFTS
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%
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产品特性
- This is a rabbit polyclonal antibody against CRYBA1. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human CRYBA1
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anti-Crystallin, beta A1 (CRYBA1) (AA 1-215) antibody
CRYBA1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Crystallin, beta A1 (CRYBA1) (AA 104-133) antibodyCRYBA1 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB31287 unconjugated
anti-Crystallin, beta A1 (CRYBA1) (AA 1-215) antibodyCRYBA1 适用: 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Crystallin, beta A1 (CRYBA1) (AA 111-141), (Middle Region) antibodyCRYBA1 适用: 人, 小鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Crystallin, beta A1 (CRYBA1) (N-Term) antibodyCRYBA1 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 兔, 马, 斑马鱼, Pig, Bat, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Crystallin, beta A1 (CRYBA1) (N-Term) antibodyCRYBA1 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Crystallin, beta A1 (CRYBA1) (AA 116-215) antibodyCRYBA1 适用: 人 ELISA, WB 宿主: 小鼠 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP52061-100UG
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- CRYBA1 (Crystallin, beta A1 (CRYBA1))
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别名
- CRYBA1
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背景
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Background Information: Crystallins are the dominant structural components of the vertebrate eye lens. Defects in CRYBA1 are the cause of congenital zonular cataract with sutural opacities (CCZS).Crystallins are separated into two classes: taxon-specific, or enzyme, and ubiquitous. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. Since lens central fiber cells lose their nuclei during development, these crystallins are made and then retained throughout life, making them extremely stable proteins. Mammalian lens crystallins are divided into alpha, beta, and gamma families, beta and gamma crystallins are also considered as a superfamily. Alpha and beta families are further divided into acidic and basic groups. Seven protein regions exist in crystallins: four homologous motifs, a connecting peptide, and N- and C-terminal extensions. Beta-crystallins, the most heterogeneous, differ by the presence of the C-terminal extension (present in the basic group, none in the acidic group). Beta-crystallins form aggregates of different sizes and are able to self-associate to form dimers or to form heterodimers with other beta-crystallins. This gene, a beta acidic group member, encodes two proteins (crystallin, beta A3 and crystallin, beta A1) from a single mRNA, the latter protein is 17 aa shorter than crystallin, beta A3 and is generated by use of an alternate translation initiation site. Deletion of exons 3 and 4 causes the autosomal dominant disease 'zonular cataract with sutural opacities'. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Gene Name: Crystallin, beta A1
Alternative Symbols: CRYB1, CTRCT10
Protein Name: Beta-crystallin A3
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分子量
- 25kDa
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基因ID
- 1411
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NCBI登录号
- NP_005199
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UniProt
- P05813
抗原
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