CLK1 抗体 (N-Term)
(2 references)Quick Overview for CLK1 抗体 (N-Term) (ABIN2784736)
抗原
See all CLK1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- HSSAQENKRC KYNHSKMCDS HYLESRSINE KDYHSRRYID EYRNDYTQGC
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 86%, Rabbit: 100%, Rat: 85%
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产品特性
- This is a rabbit polyclonal antibody against CLK1. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human CLK1
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anti-CDC like Kinase 1 (CLK1) (Internal Region) antibody
CLK1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-CDC like Kinase 1 (CLK1) (AA 1-130) antibodyCLK1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-CDC like Kinase 1 (CLK1) (N-Term) antibodyCLK1 适用: 人, 小鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-CDC like Kinase 1 (CLK1) (Internal Region) antibodyCLK1 适用: 人, 小鼠 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-CDC like Kinase 1 (CLK1) (AA 1-484) antibodyCLK1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-CDC like Kinase 1 (CLK1) (Center) antibodyCLK1 适用: 人, 猴 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-CDC like Kinase 1 (CLK1) (AA 1-130) antibodyCLK1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-CDC like Kinase 1 (CLK1) (AA 35-84) antibodyCLK1 适用: 人, 小鼠, 猴, Cow, 犬, 豚鼠, 马, 兔, 大鼠, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-CDC like Kinase 1 (CLK1) (AA 101-150) antibodyCLK1 适用: 人, 小鼠 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-CDC like Kinase 1 (CLK1) (Internal Region) antibodyCLK1 适用: 人, 小鼠 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 484 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "Release of SR Proteins from CLK1 by SRPK1: A Symbiotic Kinase System for Phosphorylation Control of Pre-mRNA Splicing." in: Molecular cell, Vol. 63, Issue 2, pp. 218-228, (2016) (PubMed).
: "Regulation of pro-angiogenic tissue factor expression in hypoxia-induced human lung cancer cells." in: Oncology reports, Vol. 30, Issue 1, pp. 462-70, (2013) (PubMed).
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: "Release of SR Proteins from CLK1 by SRPK1: A Symbiotic Kinase System for Phosphorylation Control of Pre-mRNA Splicing." in: Molecular cell, Vol. 63, Issue 2, pp. 218-228, (2016) (PubMed).
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- CLK1 (CDC like Kinase 1 (CLK1))
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别名
- CLK1
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背景
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This gene encodes a member of the CDC2-like (or LAMMER) family of dual specificity protein kinases. In the nucleus, the encoded protein phosphorylates serine/arginine-rich proteins involved in pre-mRNA processing, releasing them into the nucleoplasm. The choice of splice sites during pre-mRNA processing may be regulated by the concentration of transacting factors, including serine/arginine rich proteins. Therefore, the encoded protein may play an indirect role in governing splice site selection. Multiple transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: CLK, CLK/STY, STY
Protein Interaction Partner: KRTAP10-7, PDE9A, PRMT5, SRPK2, SRPK1, CLK1, BAG3, PIAS4, ISG15, UBC, YWHAG, LUC7L3, PPIG, SRSF6, PRPF4, GOLM1, UBL5, SRSF1, PTPN1, MBP, BCLAF1, NCOR1, SRSF3, SAFB,
Protein Size: 484 -
分子量
- 57 kDa
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基因ID
- 1195
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NCBI登录号
- NM_004071, NP_004062
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UniProt
- P49759
抗原
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