CENPB 抗体 (C-Term)
Quick Overview for CENPB 抗体 (C-Term) (ABIN2784717)
抗原
See all CENPB 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- GGEDSDSDSE EEDDEEEDDE DEDDDDDEED GDEVPVPSFG EAMAYFAMVK
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预测反应
- Cow: 83%, Horse: 86%, Human: 100%, Mouse: 93%, Pig: 86%, Rat: 100%, Sheep: 86%, Yeast: 100%, Zebrafish: 75%
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产品特性
- This is a rabbit polyclonal antibody against CENPB. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human CENPB
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anti-Centromere Protein B (CENPB) (AA 1-599) antibody
CENPB 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Centromere Protein B (CENPB) (AA 1-599) antibodyCENPB 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Centromere Protein B (CENPB) (C-Term) antibodyCENPB 适用: 人 WB, IF, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Centromere Protein B (CENPB) (AA 1-165) antibodyCENPB 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Centromere Protein B (CENPB) (C-Term) antibodyCENPB 适用: 人 IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Centromere Protein B (CENPB) (AA 506-555) antibodyCENPB 适用: 人, 马, Pig, 绵羊, 犬 WB 宿主: 兔 Polyclonal unconjugated
anti-Centromere Protein B (CENPB) antibody (PE)CENPB 适用: 人 IHC, IF, ICC, FACS 宿主: 兔 Polyclonal PE
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 599 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- CENPB (Centromere Protein B (CENPB))
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别名
- CENPB
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背景
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CENPB is a highly conserved protein that facilitates centromere formation. It is a DNA-binding protein that is derived from transposases of the pogo DNA transposon family. It contains a helix-loop-helix DNA binding motif at the N-terminus, and a dimerization domain at the C-terminus. This protein is proposed to play an important role in the assembly of specific centromere structures in interphase nuclei and on mitotic chromosomes. It is also considered a major centromere autoantigen recognized by sera from patients with anti-centromere antibodies.This gene product is a highly conserved protein that facilitates centromere formation. It is a DNA-binding protein that is derived from transposases of the pogo DNA transposon family. It contains a helix-loop-helix DNA binding motif at the N-terminus, and a dimerization domain at the C-terminus. The DNA binding domain recognizes and binds a 17-bp sequence (CENP-B box) in the centromeric alpha satellite DNA. This protein is proposed to play an important role in the assembly of specific centromere structures in interphase nuclei and on mitotic chromosomes. It is also considered a major centromere autoantigen recognized by sera from patients with anti-centromere antibodies. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: -
Protein Interaction Partner: UBC, RNF2, NR3C1, FBXO25, CENPA, APP, GFI1B, SUMO2, SMN1, PIN1, GSK3B, GADD45A, CSNK2B, CDKN1A, ANXA7, RPS6KA6, TK1, TAC1, TAF1D, PARP1, PARP2, HAND2, CENPB,
Protein Size: 599 -
分子量
- 65 kDa
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基因ID
- 1059
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NCBI登录号
- NM_001810, NP_001801
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UniProt
- P07199
抗原
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