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DPH1 抗体 (Middle Region)

This anti-DPH1 antibody is a 兔 多克隆 antibody detecting DPH1 in WB 和 IHC. Suitable for 人, 小鼠, 犬, 豚鼠, 马, 兔, 大鼠, Cow, Saccharomyces cerevisiae 和 斑马鱼.
产品编号 ABIN2784708
发货至: 中国

Quick Overview for DPH1 抗体 (Middle Region) (ABIN2784708)

抗原

See all DPH1 抗体
DPH1 (DPH1 Homolog (DPH1))

适用

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人, 小鼠, 犬, 豚鼠, 马, 兔, 大鼠, Cow, Saccharomyces cerevisiae, 斑马鱼

宿主

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克隆类型

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多克隆

标记

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This DPH1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

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    Middle Region

    序列

    RMQAARQEAI ATARSAKSWG LILGTLGRQG SPKILEHLES RLRALGLSFV

    预测反应

    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 83%, Zebrafish: 93%

    产品特性

    This is a rabbit polyclonal antibody against DPH1. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the middle region of human DPH1
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 443 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    DPH1 (DPH1 Homolog (DPH1))

    别名

    DPH1

    背景

    Diphthamide is a unique posttranslationally modified histidine found only in translation elongation factor-2 (EEF2, MIM 130610). This modification is conserved from archaebacteria to humans and serves as the target for ADP-ribosylation and inactivation of EEF2 by diphtheria toxin (DT) and Pseudomonas exotoxin A. DPH1 is 1 of several enzymes involved in synthesis of diphthamide in EEF2 (Liu et al., 2004 [PubMed 15485916]). Diphthamide is a unique posttranslationally modified histidine found only in translation elongation factor-2 (EEF2, MIM 130610). This modification is conserved from archaebacteria to humans and serves as the target for ADP-ribosylation and inactivation of EEF2 by diphtheria toxin (DT) and Pseudomonas exotoxin A. DPH1 is 1 of several enzymes involved in synthesis of diphthamide in EEF2 (Liu et al., 2004 [PubMed 15485916]).[supplied by OMIM]. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-40 AF321876.1 1-40 41-1028 BC003099.1 3-990 1029-1410 BP417755.1 78-459 1411-2188 AK090530.1 1484-2261 2189-2200 AF321876.1 2189-2200
    Alias Symbols: DPH2L, DPH2L1, FLJ33211, OVCA1
    Protein Interaction Partner: UBC, TFCP2, MMS19, UBD, TP63, TP73, TP53, RBM8A, HSPA5,
    Protein Size: 443

    分子量

    49 kDa

    基因ID

    1801

    NCBI登录号

    NM_001383, NP_001374

    UniProt

    Q9BZG8
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