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Adrenomedullin 抗体 (C-Term)

ADM 适用: 人, 兔 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2784687
发货至: 中国
  • 抗原 See all Adrenomedullin (ADM) 抗体
    Adrenomedullin (ADM)
    抗原表位
    • 15
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    • 1
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    C-Term
    适用
    • 53
    • 48
    • 13
    • 7
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    • 1
    • 1
    人, 兔
    宿主
    • 98
    • 10
    • 2
    • 1
    克隆类型
    • 101
    • 10
    多克隆
    标记
    • 45
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    • 1
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    This Adrenomedullin antibody is un-conjugated
    应用范围
    • 51
    • 38
    • 28
    • 26
    • 26
    • 12
    • 9
    • 9
    • 8
    • 8
    • 7
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    Western Blotting (WB)
    序列
    VAPRSKISPQ GYGRRRRRSL PEAGPGRTLV SSKPQAHGAP APPSGSAPHF
    预测反应
    Human: 100%, Rabbit: 91%
    产品特性
    This is a rabbit polyclonal antibody against ADM. It was validated on Western Blot.
    纯化方法
    Affinity Purified
    Top Product
    Discover our top product ADM Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 185 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    Adrenomedullin (ADM)
    别名
    ADM (ADM 产品)
    别名
    ADM antibody, Ap antibody, H39316 antibody, RATAP antibody, AM antibody, adrenomedullin antibody, ADM antibody, adm antibody, Adm antibody
    物质类
    Hormone
    背景
    Adrenomedullin, a hypotensive peptide found in human pheochromocytoma, consists of 52 amino acids, has 1 intramolecular disulfide bond, and shows a slight homology with the calcitonin gene-related peptide. It may function as a hormone in circulation control because it is found in blood in a considerable concentration. The precursor, called preproadrenomedullin, is 185 amino acids long. By RNA-blot analysis, human adrenomedullin mRNA was found to be highly expressed in several tissues. Genomic ADM DNA consists of 4 exons and 3 introns, with the 5-prime flanking region containing TATA, CAAT, and GC boxes. There are also multiple binding sites for activator protein-2 and a cAMP-regulated enhancer element.
    Alias Symbols: AM
    Protein Interaction Partner: CALCRL, EDN1, CFH, MME, ADM,
    Protein Size: 185
    分子量
    20 kDa
    基因ID
    133
    NCBI登录号
    NM_001124, NP_001115
    UniProt
    P35318
    途径
    Hormone Transport, Hormone Activity, C21-Steroid Hormone Metabolic Process, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, Tube Formation
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