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Adrenomedullin 抗体 (C-Term)

This anti-Adrenomedullin antibody is a 兔 多克隆 antibody detecting Adrenomedullin in WB. Suitable for 人 和 兔.
产品编号 ABIN2784687
发货至: 中国

Quick Overview for Adrenomedullin 抗体 (C-Term) (ABIN2784687)

抗原

See all Adrenomedullin (ADM) 抗体
Adrenomedullin (ADM)

适用

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人, 兔

宿主

  • 117
  • 22
  • 2
  • 1

克隆类型

  • 120
  • 22
多克隆

标记

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This Adrenomedullin antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    C-Term

    序列

    VAPRSKISPQ GYGRRRRRSL PEAGPGRTLV SSKPQAHGAP APPSGSAPHF

    预测反应

    Human: 100%, Rabbit: 91%

    产品特性

    This is a rabbit polyclonal antibody against ADM. It was validated on Western Blot.

    纯化方法

    Affinity Purified
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 185 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    Adrenomedullin (ADM)

    别名

    ADM

    物质类

    Hormone

    背景

    Adrenomedullin, a hypotensive peptide found in human pheochromocytoma, consists of 52 amino acids, has 1 intramolecular disulfide bond, and shows a slight homology with the calcitonin gene-related peptide. It may function as a hormone in circulation control because it is found in blood in a considerable concentration. The precursor, called preproadrenomedullin, is 185 amino acids long. By RNA-blot analysis, human adrenomedullin mRNA was found to be highly expressed in several tissues. Genomic ADM DNA consists of 4 exons and 3 introns, with the 5-prime flanking region containing TATA, CAAT, and GC boxes. There are also multiple binding sites for activator protein-2 and a cAMP-regulated enhancer element.
    Alias Symbols: AM
    Protein Interaction Partner: CALCRL, EDN1, CFH, MME, ADM,
    Protein Size: 185

    分子量

    20 kDa

    基因ID

    133

    NCBI登录号

    NM_001124, NP_001115

    UniProt

    P35318

    途径

    Hormone Transport, Hormone Activity, C21-Steroid Hormone Metabolic Process, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, Tube Formation
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