Gephyrin 抗体 (N-Term)
Quick Overview for Gephyrin 抗体 (N-Term) (ABIN2784653)
抗原
See all Gephyrin (GPHN) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- HDELEDLPSP PPPLSPPPTT SPHKQTEDKG VQCEEEEEEK KDSGVASTED
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
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产品特性
- This is a rabbit polyclonal antibody against GPHN. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human GPHN
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anti-Gephyrin (GPHN) antibody
GPHN 适用: 人, 猴 WB, IHC, FACS, IF, IHC (p) 宿主: 小鼠 Monoclonal 3B6 unconjugated
anti-Gephyrin (GPHN) antibodyGPHN 适用: 人, 大鼠, 猴 WB, FACS 宿主: 小鼠 Monoclonal 3A6 unconjugated
anti-Gephyrin (GPHN) (AA 360-460) antibodyGPHN 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Gephyrin (GPHN) antibodyGPHN 适用: 人, 小鼠, 大鼠 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Gephyrin (GPHN) (AA 677-769) antibodyGPHN 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Gephyrin (GPHN) (AA 520-769) antibodyGPHN 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Gephyrin (GPHN) (AA 437-466) antibodyGPHN 适用: 人, 小鼠 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB24625 unconjugated
anti-Gephyrin (GPHN) (AA 444-474), (Middle Region) antibodyGPHN 适用: 人, 小鼠 WB, FACS, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Gephyrin (GPHN) (AA 1-769) antibodyGPHN 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Gephyrin (GPHN) (AA 396-445) antibodyGPHN 适用: 人, 小鼠, 大鼠, 斑马鱼, 小鸡, 猴, Cow, 犬, 豚鼠, 马, 兔, 非洲爪蟾, Bat, Pig WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 736 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Gephyrin (GPHN)
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别名
- GPHN
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背景
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GPHN is a neuronal assembly protein that anchors inhibitory neurotransmitter receptors to the postsynaptic cytoskeleton via high affinity binding to a receptor subunit domain and tubulin dimers. In nonneuronal tissues, the protein is also required for molybdenum cofactor biosynthesis. Mutations in this gene may be associated with the neurological condition hyperplexia and also lead to molybdenum cofactor deficiency. Numerous alternatively spliced transcript variants encoding different isoforms have been described, however, the full-length nature of all transcript variants is not currently known. This gene encodes a neuronal assembly protein that anchors inhibitory neurotransmitter receptors to the postsynaptic cytoskeleton via high affinity binding to a receptor subunit domain and tubulin dimers. In nonneuronal tissues, the encoded protein is also required for molybdenum cofactor biosynthesis. Mutations in this gene may be associated with the neurological condition hyperplexia and also lead to molybdenum cofactor deficiency. Numerous alternatively spliced transcript variants encoding different isoforms have been described, however, the full-length nature of all transcript variants is not currently known.
Alias Symbols: GEPH, GPH, GPHRYN, KIAA1385
Protein Interaction Partner: UBC, PAAF1, BRCC3, PPP4R1, ROCK2, MTA2, SPTAN1, SPATS1, KHDRBS1, GPHN, ACADVL, PCK1, Dynll1, OTUD4, PRPF4, ENAH, GLRB, DYNLL2, GABARAP, MTOR, PIN1, ARHGEF9, TUBA4A, PFN1,
Protein Size: 736 -
分子量
- 80 kDa
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基因ID
- 10243
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NCBI登录号
- NM_001024218, NP_001019389
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UniProt
- Q9NQX3
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途径
- Synaptic Membrane, Skeletal Muscle Fiber Development
抗原
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