Dynamin 1 抗体 (Middle Region)
Our Local Distributor
北京 101111
Quick Overview for Dynamin 1 抗体 (Middle Region) (ABIN2784624)
抗原
See all Dynamin 1 (DNM1) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- Middle Region
-
原理
- DNM1 Antibody - middle region
-
序列
- PPVDDSWLQV QSVPAGRRSP TSSPTPQRRA PAVPPARPGS RGPAPGPPPA
-
预测反应
- Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 86%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 86%
-
产品特性
- This is a rabbit polyclonal antibody against DNM1. It was validated on Western Blot using a cell lysate as a positive control.
-
纯化方法
- Affinity Purified
-
免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human DNM1
-
-
-
-
应用备注
- Optimal working dilution should be determined by the investigator.
-
说明
-
We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP51787-100UG
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 0.5 mg/mL
-
缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- prevent freeze-thaw cycles
-
储存条件
- 4 °C,-20 °C
-
储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
-
-
- Dynamin 1 (DNM1)
-
别名
- DNM1
-
背景
-
Background Information: DNM1 is a member of the dynamin subfamily of GTP-binding proteins. The protein possesses unique mechanochemical properties used to tubulate and sever membranes, and is involved in clathrin-mediated endocytosis and other vesicular trafficking processes. Actin and other cytoskeletal proteins act as binding partners for the protein, which can also self-assemble leading to stimulation of GTPase activity. More than sixty highly conserved copies of the 3' region of this gene are found elsewhere in the genome, particularly on chromosomes Y and 15. Alternatively spliced transcript variants encoding different isoforms have been described.This gene encodes a member of the dynamin subfamily of GTP-binding proteins. The encoded protein possesses unique mechanochemical properties used to tubulate and sever membranes, and is involved in clathrin-mediated endocytosis and other vesicular trafficking processes. Actin and other cytoskeletal proteins act as binding partners for the encoded protein, which can also self-assemble leading to stimulation of GTPase activity. More than sixty highly conserved copies of the 3' region of this gene are found elsewhere in the genome, particularly on chromosomes Y and 15. Alternatively spliced transcript variants encoding different isoforms have been described.
Gene Name: Dynamin 1
Alternative Symbols: DNM, DEE31, EIEE31
Protein Name: Dynamin-1
-
分子量
- 95kDa
-
基因ID
- 1759
-
NCBI登录号
- NP_004399
-
UniProt
- P39053
-
途径
- Toll-Like Receptors Cascades, CXCR4-mediated Signaling Events, Thromboxane A2 Receptor Signaling
抗原
-