Synovial Sarcoma, X Breakpoint 2B (SSX2B) (N-Term) 抗体
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Quick Overview for Synovial Sarcoma, X Breakpoint 2B (SSX2B) (N-Term) 抗体 (ABIN2784591)
抗原
See all Synovial Sarcoma, X Breakpoint 2B (SSX2B) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- IQKAFDDIAK YFSKEEWEKM KASEKIFYVY MKRKYEAMTK LGFKATLPPF
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预测反应
- Dog: 75%, Human: 100%, Mouse: 82%, Pig: 85%
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产品特性
- This is a rabbit polyclonal antibody against SSX2B. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N-terminal region of Human SSX2B
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeat freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Synovial Sarcoma, X Breakpoint 2B (SSX2B)
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别名
- SSX2B
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背景
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The product of this gene belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneous humoral and cellular immune responses in cancer patients, and are potentially useful targets in cancer vaccine-based immunotherapy. This gene, and also the SSX1 and SSX4 family members, have been involved in t(X,18)(p11.2,q11.2) translocations that are characteristically found in all synovial sarcomas. This translocation results in the fusion of the synovial sarcoma translocation gene on chromosome 18 to one of the SSX genes on chromosome X. The encoded hybrid proteins are likely responsible for transforming activity. Alternative splicing of this gene results in multiple transcript variants. This gene also has an identical duplicate, GeneID: 6757, located about 45 kb upstream in the opposite orientation on chromosome X.
Protein Size: 223 -
分子量
- 24 kDa
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基因ID
- 727837
抗原
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