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MBNL2 抗体 (Middle Region)

This anti-MBNL2 antibody is a 兔 多克隆 antibody detecting MBNL2 in WB. Suitable for 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 兔, 斑马鱼 和 马.
产品编号 ABIN2784554
发货至: 中国

Quick Overview for MBNL2 抗体 (Middle Region) (ABIN2784554)

抗原

See all MBNL2 抗体
MBNL2 (Muscleblind-Like 2 (MBNL2))

适用

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人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 兔, 斑马鱼, 马

宿主

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克隆类型

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多克隆

标记

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This MBNL2 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    Middle Region

    序列

    ENGRVIACFD SLKGRCSREN CKYLHPPTHL KTQLEINGRN NLIQQKTAAA

    预测反应

    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

    产品特性

    This is a rabbit polyclonal antibody against MBNL2. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the middle region of human MBNL2
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 255 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    MBNL2 (Muscleblind-Like 2 (MBNL2))

    别名

    MBNL2

    背景

    MBNL2 is a C3H-type zinc finger protein, which is similar to the Drosophila melanogaster muscleblind B protein.MBNL2 is a RNA-binding protein that binds to 5'ACACCC-3' core sequence. It binds to CUG triplet repeat expansion in myotonic dystrophy muscle cells by sequestering the target RNAs. MBNL2 seems to regulate expression and localization of ITGA3 by transporting it from the nucleus to cytoplasm. It may play a role in myotonic dystrophy pathophysiology (DM).
    Alias Symbols: DKFZp781H1296, MBLL, MBLL39, MGC120625, MGC120626, MGC120628, PRO2032, RP11-128N14.1
    Protein Interaction Partner: BMI1, ELAVL1, UBC,
    Protein Size: 255

    分子量

    28 kDa

    基因ID

    10150

    NCBI登录号

    NM_005757, NP_005748

    UniProt

    O95205
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