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PPIA 抗体 (Middle Region)

This anti-PPIA antibody is a 兔 多克隆 antibody detecting PPIA in WB 和 IHC. Suitable for 人, 小鼠, 大鼠, Cow, 犬, 山羊, 豚鼠, 马, 兔 和 绵羊.
产品编号 ABIN2784530
发货至: 中国

Quick Overview for PPIA 抗体 (Middle Region) (ABIN2784530)

抗原

See all PPIA 抗体
PPIA (Peptidylprolyl Isomerase A (Cyclophilin A) (PPIA))

适用

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人, 小鼠, 大鼠, Cow, 犬, 山羊, 豚鼠, 马, 兔, 绵羊

宿主

  • 135
  • 35
  • 3
  • 1

克隆类型

  • 122
  • 52
多克隆

标记

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This PPIA antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

    • 23
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    Middle Region

    序列

    TAKTEWLDGK HVVFGKVKEG MNIVEAMERF GSRNGKTSKK ITIADCGQLE

    预测反应

    Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 86%, Rat: 100%, Sheep: 100%

    产品特性

    This is a rabbit polyclonal antibody against PPIA. It was validated on Western Blot and immunohistochemistry.

    纯化方法

    Protein A purified

    免疫原

    The immunogen is a synthetic peptide directed towards the middle region of human PPIA
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 165 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    PPIA (Peptidylprolyl Isomerase A (Cyclophilin A) (PPIA))

    别名

    PPIA

    背景

    PPIA is a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. PPIA is a cyclosporin binding-protein and may play a role in cyclosporin A-mediated immunosuppression. The protein can also interact with several HIV proteins, including p55 gag, Vpr, and capsid protein, and has been shown to be necessary for the formation of infectious HIV virions.The protein encoded by this gene is a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. This protein is a cyclosporin binding-protein. It may play a role in cyclosporin A-mediated immunosuppression. This protein can interact with several HIV proteins including p55 gag, Vpr, and capsid protein. It has been shown to be necessary for the formation of infectious HIV virions. Multiple pseudogenes that map to different chromosomes have been reported. Three alternatively spliced transcript variants encoding two distinct isoforms have been observed.
    Alias Symbols: CYPA, CYPH, MGC117158, MGC12404, MGC23397
    Protein Interaction Partner: LNX1, HUWE1, UBC, TCF4, FUS, gag, MDM2, RPL23A, SRPK2, SRPK1, ESR1, UBD, TERT, RAD52, VCAM1, ITGA4, FN1, HCVgp1, LIG4, PAXIP1, RB1, APP, CPLX1, SNX3, TAGLN2, SOD1, RPA2, RAD23B, PTMA, IGBP1, ENO1, AKT1, USP4, CDK2, COPS5, CUL1, CUL3, CUL4B, NEDD8, CD99, C
    Protein Size: 165

    分子量

    18 kDa

    基因ID

    5478

    NCBI登录号

    NM_021130, NP_066953

    UniProt

    P62937
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