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TGIF1 抗体 (C-Term)

TGIF1 适用: 人, 小鼠, 大鼠, 马, 兔, Cow, 犬, Pig, 绵羊 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2784526
发货至: 中国
  • 抗原 See all TGIF1 抗体
    TGIF1 (TGFB-Induced Factor Homeobox 1 (TGIF1))
    抗原表位
    • 9
    • 8
    • 6
    • 6
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    人, 小鼠, 大鼠, 马, 兔, Cow, 犬, Pig, 绵羊
    宿主
    • 41
    • 6
    • 1
    克隆类型
    • 43
    • 5
    多克隆
    标记
    • 27
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TGIF1 antibody is un-conjugated
    应用范围
    • 33
    • 27
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    序列
    GQNTDIQQIA AKNFTDTSLM YPEDTCKSGP STNTQSGLFN TPPPTPPDLN
    预测反应
    Cow: 93%, Dog: 93%, Horse: 100%, Human: 100%, Mouse: 86%, Pig: 93%, Rabbit: 100%, Rat: 86%, Sheep: 93%
    产品特性
    This is a rabbit polyclonal antibody against TGIF1. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the C terminal region of human TGIF1
    Top Product
    Discover our top product TGIF1 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 401 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    TGIF1 (TGFB-Induced Factor Homeobox 1 (TGIF1))
    别名
    TGIF1 (TGIF1 产品)
    别名
    HPE4 antibody, TGIF antibody, AA959811 antibody, AI462167 antibody, Tgif antibody, Tfig antibody, fa06h05 antibody, fb33g11 antibody, zgc:55852 antibody, wu:fa06h05 antibody, wu:fb33g11 antibody, hpe4 antibody, tgif antibody, tgif1 antibody, TGFB induced factor homeobox 1 antibody, TGFB-induced factor homeobox 1 antibody, TGFB induced factor homeobox 1 S homeolog antibody, TGIF1 antibody, Tgif1 antibody, tgif1 antibody, tgif1.S antibody
    背景
    TGIF1 is a member of the three-amino acid loop extension (TALE) superclass of atypical homeodomains. TALE homeobox proteins are highly conserved transcription regulators. This particular homeodomain binds to a previously characterized retinoid X receptor responsive element from the cellular retinol-binding protein II promoter. In addition to its role in inhibiting 9-cis-retinoic acid-dependent RXR alpha transcription activation of the retinoic acid responsive element, the protein is an active transcriptional co-repressor of SMAD2 and may participate in the transmission of nuclear signals during development and in the adult. Mutations in this gene are associated with holoprosencephaly type 4, which is a structural anomaly of the brain.The protein encoded by this gene is a member of the three-amino acid loop extension (TALE) superclass of atypical homeodomains. TALE homeobox proteins are highly conserved transcription regulators. This particular homeodomain binds to a previously characterized retinoid X receptor responsive element from the cellular retinol-binding protein II promoter. In addition to its role in inhibiting 9-cis-retinoic acid-dependent RXR alpha transcription activation of the retinoic acid responsive element, the protein is an active transcriptional co-repressor of SMAD2 and may participate in the transmission of nuclear signals during development and in the adult. Mutations in this gene are associated with holoprosencephaly type 4, which is a structural anomaly of the brain. Alternative splicing has been observed at this locus and eight variants, encoding four distinct isoforms, are described.
    Alias Symbols: HPE4, MGC39747, MGC5066, TGIF
    Protein Interaction Partner: MDFI, CTBP2, CTBP1, APP, PML, ELAVL1, HDAC1, A2M, AR, SIN3A, SMAD3, LRIF1, MED31, MAPK3, SMAD2, MAPK1, JUN, HMGB1, EEF1A1, FOXH1, SMAD1, SDAD1, STK16, MKKS,
    Protein Size: 401
    分子量
    43 kDa
    基因ID
    7050
    NCBI登录号
    NM_170695, NP_733796
    UniProt
    Q15583
    途径
    Retinoic Acid Receptor Signaling Pathway, Chromatin Binding, Tube Formation
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