TGIF1 抗体 (C-Term)
Quick Overview for TGIF1 抗体 (C-Term) (ABIN2784526)
抗原
See all TGIF1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- GQNTDIQQIA AKNFTDTSLM YPEDTCKSGP STNTQSGLFN TPPPTPPDLN
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预测反应
- Cow: 93%, Dog: 93%, Horse: 100%, Human: 100%, Mouse: 86%, Pig: 93%, Rabbit: 100%, Rat: 86%, Sheep: 93%
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产品特性
- This is a rabbit polyclonal antibody against TGIF1. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human TGIF1
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anti-TGFB-Induced Factor Homeobox 1 (TGIF1) (AA 8-375) antibody
TGIF1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-TGFB-Induced Factor Homeobox 1 (TGIF1) (C-Term) antibodyTGIF1 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-TGFB-Induced Factor Homeobox 1 (TGIF1) (AA 163-272) antibodyTGIF1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-TGFB-Induced Factor Homeobox 1 (TGIF1) (AA 163-272) antibodyTGIF1 适用: 人 ELISA 宿主: 小鼠 Monoclonal 1D12 unconjugated
anti-TGFB-Induced Factor Homeobox 1 (TGIF1) (AA 324-373) antibodyTGIF1 适用: 人, 小鼠, 大鼠, 马, 兔, Bat, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-TGFB-Induced Factor Homeobox 1 (TGIF1) (AA 123-272) antibodyTGIF1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-TGFB-Induced Factor Homeobox 1 (TGIF1) (AA 208-237) antibodyTGIF1 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB14110 unconjugated
anti-TGFB-Induced Factor Homeobox 1 (TGIF1) (AA 215-245), (Middle Region) antibodyTGIF1 适用: 人, 小鼠 WB, EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 401 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- TGIF1 (TGFB-Induced Factor Homeobox 1 (TGIF1))
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别名
- TGIF1
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背景
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TGIF1 is a member of the three-amino acid loop extension (TALE) superclass of atypical homeodomains. TALE homeobox proteins are highly conserved transcription regulators. This particular homeodomain binds to a previously characterized retinoid X receptor responsive element from the cellular retinol-binding protein II promoter. In addition to its role in inhibiting 9-cis-retinoic acid-dependent RXR alpha transcription activation of the retinoic acid responsive element, the protein is an active transcriptional co-repressor of SMAD2 and may participate in the transmission of nuclear signals during development and in the adult. Mutations in this gene are associated with holoprosencephaly type 4, which is a structural anomaly of the brain.The protein encoded by this gene is a member of the three-amino acid loop extension (TALE) superclass of atypical homeodomains. TALE homeobox proteins are highly conserved transcription regulators. This particular homeodomain binds to a previously characterized retinoid X receptor responsive element from the cellular retinol-binding protein II promoter. In addition to its role in inhibiting 9-cis-retinoic acid-dependent RXR alpha transcription activation of the retinoic acid responsive element, the protein is an active transcriptional co-repressor of SMAD2 and may participate in the transmission of nuclear signals during development and in the adult. Mutations in this gene are associated with holoprosencephaly type 4, which is a structural anomaly of the brain. Alternative splicing has been observed at this locus and eight variants, encoding four distinct isoforms, are described.
Alias Symbols: HPE4, MGC39747, MGC5066, TGIF
Protein Interaction Partner: MDFI, CTBP2, CTBP1, APP, PML, ELAVL1, HDAC1, A2M, AR, SIN3A, SMAD3, LRIF1, MED31, MAPK3, SMAD2, MAPK1, JUN, HMGB1, EEF1A1, FOXH1, SMAD1, SDAD1, STK16, MKKS,
Protein Size: 401 -
分子量
- 43 kDa
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基因ID
- 7050
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NCBI登录号
- NM_170695, NP_733796
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UniProt
- Q15583
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途径
- Retinoic Acid Receptor Signaling Pathway, Chromatin Binding, Tube Formation
抗原
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