Frataxin 抗体 (C-Term)
Quick Overview for Frataxin 抗体 (C-Term) (ABIN2784465)
抗原
See all Frataxin (FXN) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
 - C-Term
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序列
 - EFFEDLADKP YTLKDYDVSF GDGVLTIKLG GDLGTYVINK QTPNKQIWLS
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预测反应
 - Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 92%, Zebrafish: 92%
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产品特性
 - This is a rabbit polyclonal antibody against Fxn. It was validated on Western Blot.
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纯化方法
 - Affinity Purified
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免疫原
 - The immunogen is a synthetic peptide corresponding to a region of Rat
 
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应用备注
 - Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 208 AA
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限制
 - 仅限研究用
 
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状态
 - Liquid
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浓度
 - Lot specific
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缓冲液
 - Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
 - Sodium azide
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注意事项
 - This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
 - Avoid repeated freeze-thaw cycles.
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储存条件
 - -20 °C
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储存方法
 - For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
 
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- Frataxin (FXN)
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别名
 - Fxn
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背景
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                        Fxn promotes the biosynthesis of heme and assembly and repair of iron-sulfur clusters by delivering Fe2+ to proteins involved in these pathways. It may play a role in the protection against iron-catalyzed oxidative stress through its ability to catalyze the oxidation of Fe2+ to Fe3+, the oligomeric form but not the monomeric form has in vitro ferroxidase activity. It may be able to store large amounts of iron in the form of a ferrihydrite mineral by oligomerization. Fxn modulates the RNA-binding activity of ACO1.
Alias Symbols: RGD1565754, Fxn
Protein Size: 208 - 
                                            
分子量
 - 23 kDa
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基因ID
 - 499335
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NCBI登录号
 - NM_001191952, XP_001078791
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UniProt
 - D3ZYW7
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途径
 - Transition Metal Ion Homeostasis, Regulation of Cell Size
 
抗原
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