PYHIN1 抗体 (N-Term)
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北京 101111
Quick Overview for PYHIN1 抗体 (N-Term) (ABIN2784367)
抗原
See all PYHIN1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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原理
- PYHIN1 Antibody - N-terminal region
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序列
- ANNYKKIVLL KGLEVINDYH FRIVKSLLSN DLKLNPKMKE EYDKIQIADL
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预测反应
- Cow: 91%, Dog: 91%, Horse: 91%, Human: 100%, Mouse: 100%, Pig: 85%, Rabbit: 93%, Rat: 85%
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产品特性
- This is a rabbit polyclonal antibody against PYHIN1. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human PYHIN1
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anti-Pyrin and HIN Domain Family, Member 1 (PYHIN1) (AA 26-55), (N-Term) antibody
PYHIN1 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB26421 unconjugated
anti-Pyrin and HIN Domain Family, Member 1 (PYHIN1) (AA 38-87) antibodyPYHIN1 适用: 人, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Pyrin and HIN Domain Family, Member 1 (PYHIN1) (N-Term) antibodyPYHIN1 适用: 人, 小鼠, 大鼠, Cow, 犬 WB 宿主: 兔 Polyclonal unconjugated
anti-Pyrin and HIN Domain Family, Member 1 (PYHIN1) (AA 1-245) antibodyPYHIN1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP50875-100UG
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- PYHIN1 (Pyrin and HIN Domain Family, Member 1 (PYHIN1))
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别名
- PYHIN1
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背景
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Background Information: PYHIN1 belongs to the HIN-200 family. This protein is major mediator of the tumor suppressor activity of IFN in breast cancer cells. It promotes ubiquitination and subsequent degradation of MDM2, which leads to p53/TP53 stabilization, and HDAC1, which in turn enhances maspin expression, and impairs invasive activity of cancer cells.
Gene Name: Pyrin and HIN domain family, member 1
Alternative Symbols: IFIX
Protein Name: Pyrin and HIN domain-containing protein 1
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分子量
- 55kDa
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基因ID
- 149628
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NCBI登录号
- NP_689714
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UniProt
- Q6K0P9
抗原
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