PYHIN1 抗体 (N-Term)
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- 抗原 See all PYHIN1 抗体
- PYHIN1 (Pyrin and HIN Domain Family, Member 1 (PYHIN1))
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抗原表位
- N-Term
- 适用
- 人, 小鼠, 大鼠, Cow, 犬, Pig, 兔, 马
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PYHIN1 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- ANNYKKIVLL KGLEVINDYH FRIVKSLLSN DLKLNPKMKE EYDKIQIADL
- 预测反应
- Cow: 91%, Dog: 91%, Horse: 91%, Human: 100%, Mouse: 100%, Pig: 85%, Rabbit: 93%, Rat: 85%
- 产品特性
- This is a rabbit polyclonal antibody against PYHIN1. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human PYHIN1
- Top Product
- Discover our top product PYHIN1 Primary Antibody
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anti-Pyrin and HIN Domain Family, Member 1 (PYHIN1) (AA 26-55), (N-Term) antibody
PYHIN1 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB26421 unconjugated
anti-Pyrin and HIN Domain Family, Member 1 (PYHIN1) (AA 1-245) antibodyPYHIN1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Pyrin and HIN Domain Family, Member 1 (PYHIN1) (AA 38-87) antibodyPYHIN1 适用: 人, 猴 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 492 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- PYHIN1 (Pyrin and HIN Domain Family, Member 1 (PYHIN1))
- 别名
- PYHIN1 (PYHIN1 产品)
- 别名
- IFIX antibody, RP11-520H16.1 antibody, 4930422C14 antibody, AI447904 antibody, Ifi209 antibody, Ifix antibody, pyrin and HIN domain family member 1 antibody, interferon activated gene 209 antibody, PYHIN1 antibody, Ifi209 antibody
- 背景
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PYHIN1 belongs to the HIN-200 family. This protein is major mediator of the tumor suppressor activity of IFN in breast cancer cells. It promotes ubiquitination and subsequent degradation of MDM2, which leads to p53/TP53 stabilization, and HDAC1, which in turn enhances maspin expression, and impairs invasive activity of cancer cells.
Alias Symbols: IFIX, MGC23885, RP11-520H16.1
Protein Interaction Partner: MDM2,
Protein Size: 492 - 分子量
- 55 kDa
- 基因ID
- 149628
- NCBI登录号
- NM_152501, NP_689714
- UniProt
- Q6K0P9
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