PYHIN1 抗体 (N-Term)
Quick Overview for PYHIN1 抗体 (N-Term) (ABIN2784367)
抗原
See all PYHIN1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- N-Term
-
序列
- ANNYKKIVLL KGLEVINDYH FRIVKSLLSN DLKLNPKMKE EYDKIQIADL
-
预测反应
- Cow: 91%, Dog: 91%, Horse: 91%, Human: 100%, Mouse: 100%, Pig: 85%, Rabbit: 93%, Rat: 85%
-
产品特性
- This is a rabbit polyclonal antibody against PYHIN1. It was validated on Western Blot using a cell lysate as a positive control.
-
纯化方法
- Affinity Purified
-
免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human PYHIN1
-
-
anti-Pyrin and HIN Domain Family, Member 1 (PYHIN1) (AA 26-55), (N-Term) antibody
PYHIN1 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB26421 unconjugated
anti-Pyrin and HIN Domain Family, Member 1 (PYHIN1) (AA 1-245) antibodyPYHIN1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Pyrin and HIN Domain Family, Member 1 (PYHIN1) (AA 38-87) antibodyPYHIN1 适用: 人, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Pyrin and HIN Domain Family, Member 1 (PYHIN1) (N-Term) antibodyPYHIN1 适用: 人, 小鼠, 大鼠, Cow, 犬 WB 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
-
说明
-
Antigen size: 492 AA
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- Lot specific
-
缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freeze-thaw cycles.
-
储存条件
- -20 °C
-
储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
-
- PYHIN1 (Pyrin and HIN Domain Family, Member 1 (PYHIN1))
-
别名
- PYHIN1
-
背景
-
PYHIN1 belongs to the HIN-200 family. This protein is major mediator of the tumor suppressor activity of IFN in breast cancer cells. It promotes ubiquitination and subsequent degradation of MDM2, which leads to p53/TP53 stabilization, and HDAC1, which in turn enhances maspin expression, and impairs invasive activity of cancer cells.
Alias Symbols: IFIX, MGC23885, RP11-520H16.1
Protein Interaction Partner: MDM2,
Protein Size: 492 -
分子量
- 55 kDa
-
基因ID
- 149628
-
NCBI登录号
- NM_152501, NP_689714
-
UniProt
- Q6K0P9
抗原
-
