URI1 抗体 (Middle Region)
Quick Overview for URI1 抗体 (Middle Region) (ABIN2784320)
抗原
See all URI1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- NGEYVPRKSI LKSRSRENSV CSDTSESSAA EFDDRRGVLR SISCEEATCS
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预测反应
- Cow: 93%, Dog: 86%, Guinea Pig: 93%, Horse: 86%, Human: 100%, Mouse: 79%, Rabbit: 100%, Rat: 80%
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产品特性
- This is a rabbit polyclonal antibody against C19orf2. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human C19orf2
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 495 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- URI1 (URI1, Prefoldin-Like Chaperone (URI1))
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别名
- C19orf2
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背景
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The function of the C19orf2 protein remains unknown.The protein encoded by this gene binds to RNA polymerase II subunit 5 (RPB5) and negatively modulates transcription through its binding to RPB5. The encoded protein seems to have inhibitory effects on various types of activated transcription, but it requires the RPB5-binding region. This protein acts as a corepressor. It is suggested that it may require signaling processes for its function or that it negatively modulates genes in the chromatin structure. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Alias Symbols: FLJ10575, NNX3, RMP, URI, C19orf2, PPP1R19
Protein Interaction Partner: RPAP3, UBC, ITCH, NEDD4, ATF7, TTI1, RUVBL1, RPS6KB1, PPP1CC, HSP90AA1, APP, UXT, RPAP2, GPN1, RUVBL2, STAP1, POLR2E, URI1, DMAP1, GTF2F2,
Protein Size: 495 -
分子量
- 55 kDa
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基因ID
- 8725
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NCBI登录号
- NM_134447, NP_604431
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UniProt
- Q6NX55
抗原
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