SIN3B 抗体 (Middle Region)
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北京 101111
Quick Overview for SIN3B 抗体 (Middle Region) (ABIN2784242)
抗原
See all SIN3B 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- NDTKALRSKS LLNEIESVYD EHQEQHSEGR SAPSSEPHLI FVYEDRQILE
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 86%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 93%
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产品特性
- This is a rabbit polyclonal antibody against SIN3B. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human SIN3B
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anti-SIN3 Transcription Regulator Homolog B (SIN3B) (Internal Region) antibody
SIN3B 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-SIN3 Transcription Regulator Homolog B (SIN3B) (AA 705-769) antibodySIN3B 适用: 人 ELISA, IF, IHC 宿主: 兔 Polyclonal unconjugated
anti-SIN3 Transcription Regulator Homolog B (SIN3B) (AA 1063-1160) antibodySIN3B 适用: 人 ELISA 宿主: 小鼠 Monoclonal 2C11 unconjugated
anti-SIN3 Transcription Regulator Homolog B (SIN3B) (AA 1-353) antibodySIN3B 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-SIN3 Transcription Regulator Homolog B (SIN3B) (AA 900-949) antibodySIN3B 适用: 人, 小鼠, Cow, 犬, 马, Pig, 猴, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-SIN3 Transcription Regulator Homolog B (SIN3B) (AA 220-269) antibodySIN3B 适用: 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-SIN3 Transcription Regulator Homolog B (SIN3B) (AA 614-663) antibodySIN3B 适用: 人, 小鼠, Cow, 犬, 马, Pig, 猴, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-SIN3 Transcription Regulator Homolog B (SIN3B) (N-Term) antibodySIN3B 适用: 人, 小鼠, 大鼠, Cow WB 宿主: 兔 Polyclonal unconjugated
anti-SIN3 Transcription Regulator Homolog B (SIN3B) (Middle Region) antibodySIN3B 适用: 人, 小鼠, Cow, 斑马鱼, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-SIN3 Transcription Regulator Homolog B (SIN3B) (N-Term) antibodySIN3B 适用: 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 1162 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "The human SIN3B corepressor forms a nucleolar complex with leukemia-associated ETO homologues." in: BMC molecular biology, Vol. 9, pp. 8, (2008) (PubMed).
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: "The human SIN3B corepressor forms a nucleolar complex with leukemia-associated ETO homologues." in: BMC molecular biology, Vol. 9, pp. 8, (2008) (PubMed).
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- SIN3B (SIN3 Transcription Regulator Homolog B (SIN3B))
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别名
- SIN3B
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背景
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SIN3B acts as a transcriptional repressor. It interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities.It also interacts with MAD-MAX heterodimers by binding to MAD. The heterodimer then represses transcription by tethering SIN3B to DNA. SIN3B also forms a complex with FOXK1 which represses transcription.
Alias Symbols: KIAA0700
Protein Interaction Partner: SOX2, HDAC1, HDAC2, UBC, ESR1, AR, TFAP4, TP53, SUMO2, KLF16, MORF4L1, MORF4L2, MRGBP, KDM5A, CIITA, NR1D2, COPS2, SMN1, PBX1, REST, ZBTB4, ARID4A, MYT1, MXI1, SAP25, SMARCE1, SMARCB1, SMARCA4, SMARCA2, CBFA2T3, RNF220, ZBTB16, SETDB1, HDAC9, IKZF4, IKZF1
Protein Size: 1162 -
分子量
- 133 kDa
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基因ID
- 23309
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NCBI登录号
- NM_015260, NP_056075
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UniProt
- O75182
抗原
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