TRAPPC2 抗体 (Middle Region)
Our Local Distributor
北京 101111
Quick Overview for TRAPPC2 抗体 (Middle Region) (ABIN2784240)
抗原
See all TRAPPC2 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- Middle Region
-
原理
- TRAPPC2 Antibody - middle region
-
序列
- RQEDGIKNFF TDVYDLYIKF SMNPFYEPNS PIRSSAFDRK VQFLGKKHLL
-
预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 86%, Rat: 100%
-
产品特性
- This is a rabbit polyclonal antibody against TRAPPC2. It was validated on Western Blot using a cell lysate as a positive control.
-
纯化方法
- Affinity Purified
-
免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human TRAPPC2
-
-
-
-
应用备注
- Optimal working dilution should be determined by the investigator.
-
说明
-
We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP50568-100UG
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 0.5 mg/mL
-
缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- prevent freeze-thaw cycles
-
储存条件
- 4 °C,-20 °C
-
储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
-
-
- TRAPPC2 (Trafficking Protein Particle Complex 2 (TRAPPC2))
-
别名
- TRAPPC2
-
背景
-
Targeted Subunit: 2
Background Information: TRAPPC2 prevents MBP1-mediated transcriptional repression and antagonizes MBP1-mediated cell death. TRAPPC2 may play a role in vesicular transport from endoplasmic reticulum to Golgi.The protein encoded by this gene is thought to be part of a large multisubunit complex involved in the targeting and fusion of endoplasmic reticulum-to-Golgi transport vesicles with their acceptor compartment. In addition, the encoded protein can bind MBP1 and block its transcriptional repression capability. Mutations in this gene are a cause of spondyloepiphyseal dysplasia tarda (SEDT). A processed pseudogene of this gene is located on chromosome 19, and other pseuodogenes are found on chromosomes 8 and Y. Alternatively spliced transcript variants encoding distinct isoforms or having different 5' UTRs, have been found for this gene.
Gene Name: Trafficking protein particle complex 2
Alternative Symbols: SEDL, SEDT, MIP2A, TRS20, ZNF547L, hYP38334, TRAPPC2P1
-
分子量
- 16kDa
-
基因ID
- 6399
-
NCBI登录号
- NP_055378
-
UniProt
- O14582
抗原
-