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SPRY2 抗体 (N-Term)

Name: SPRY2 抗体 (N-Term)
SKU: ABIN2784217
Availability: OutOfStock

This anti-SPRY2 antibody is a 兔多克隆 antibody detecting SPRY2 in WB 和 IHC. Suitable for 人, 小鼠, 大鼠, 犬, Cow, 马, 兔, Pig 和豚鼠. This Primary Antibody has been cited in 1 publication.

WB Suggested Anti-SPRY2 Antibody Titration: 0. (SPRY2 抗体 (N-Term))

Rabbit Anti-SPRY2 Antibody Formalin Fixed Paraffin Embedded Tissue: Human heart Tissue Observed Staining: Cytoplasmic in vasculature Primary Antibody Concentration: 1:100 Other Working Concentrations: 1:600 Secondary Antibody: Donkey anti-Rabbit-Cy3 Secondary Antibody Concentration: 1:200 Magnification: 20X Exposure Time: 0. (SPRY2 抗体 (N-Term))

IHC

2 images

(1 reference)

产品编号 ABIN2784217

发货至: 中国

Quick Overview for SPRY2 抗体 (N-Term) (ABIN2784217)

抗原

See all SPRY2 抗体

SPRY2 (Sprouty Homolog 2 (SPRY2))

适用

人, 小鼠, 大鼠, 犬, Cow, 马, 兔, Pig, 豚鼠

宿主

兔

克隆类型

多克隆

标记

This SPRY2 antibody is un-conjugated

应用范围

Western Blotting (WB), Immunohistochemistry (IHC)

Discover our top product SPRY2 Primary Antibody

抗原表位
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N-Term

序列

MEARAQSGNG SQPLLQTPRD GGRQRGEPDP RDALTQQVHV LSLDQIRAIR

预测反应

Cow: 93%, Dog: 100%, Guinea Pig: 92%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 86%, Rat: 100%

产品特性

This is a rabbit polyclonal antibody against SPRY2. It was validated on Western Blot using a cell lysate as a positive control.

纯化方法

Affinity Purified

免疫原

The immunogen is a synthetic peptide directed towards the N terminal region of human SPRY2
anti-Sprouty Homolog 2 (SPRY2) (AA 1-315) antibody
SPRY2 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 1E10 unconjugated

anti-Sprouty Homolog 2 (SPRY2) (AA 2-97) antibody
SPRY2 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Sprouty Homolog 2 (SPRY2) antibody
SPRY2 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated

anti-Sprouty Homolog 2 (SPRY2) (AA 107-156) antibody
SPRY2 适用: 人, 小鼠, 大鼠, 犬, Cow, 马, 兔, Pig, Hamster, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Sprouty Homolog 2 (SPRY2) (AA 1-315) antibody
SPRY2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated

anti-Sprouty Homolog 2 (SPRY2) (AA 116-305) antibody
SPRY2 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Sprouty Homolog 2 (SPRY2) (AA 116-304) antibody
SPRY2 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Sprouty Homolog 2 (SPRY2) antibody
SPRY2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Sprouty Homolog 2 (SPRY2) (AA 1-315) antibody
SPRY2 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated

anti-Sprouty Homolog 2 (SPRY2) (N-Term) antibody
SPRY2 适用: 人, 小鼠, 大鼠, 犬, Pig, Hamster WB 宿主: 兔 Polyclonal unconjugated

应用备注

Optimal working dilutions should be determined experimentally by the investigator.

说明

Antigen size: 315 AA

限制

仅限研究用
状态

Liquid

浓度

Lot specific

缓冲液

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freeze-thaw cycles.

储存条件

-20 °C

储存方法

For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Hsu, Lee, Hartstein, Harocopos: "Clostridium perfringens Keratitis Leading to Blinding Panophthalmitis." in: Cornea, Vol. 27, Issue 10, pp. 1200-3, (2008) (PubMed).
抗原

SPRY2 (Sprouty Homolog 2 (SPRY2))

别名

SPRY2

背景

SPRY2 is a protein belonging to the sprouty family. It contains a carboxyl-terminal cysteine-rich domain essential for the inhibitory activity on receptor tyrosine kinase signaling proteins and is required for growth factor stimulated translocation of the protein to membrane ruffles. In primary dermal endothelial cells this gene is transiently upregulated in response to fibroblast growth factor two. SPRY2 is indirectly involved in the non-cell autonomous inhibitory effect on fibroblast growth factor two signaling. The protein interacts with Cas-Br-M (murine) ectropic retroviral transforming sequence, and can function as a bimodal regulator of epidermal growth factor receptor/mitogen-activated protein kinase signaling. SPRY2 may play a role in alveoli branching during lung development as shown by a similar mouse protein.This gene encodes a protein belonging to the sprouty family. The encoded protein contains a carboxyl-terminal cysteine-rich domain essential for the inhibitory activity on receptor tyrosine kinase signaling proteins and is required for growth factor stimulated translocation of the protein to membrane ruffles. In primary dermal endothelial cells this gene is transiently upregulated in response to fibroblast growth factor two. This protein is indirectly involved in the non-cell autonomous inhibitory effect on fibroblast growth factor two signaling. The protein interacts with Cas-Br-M (murine) ectropic retroviral transforming sequence, and can function as a bimodal regulator of epidermal growth factor receptor/mitogen-activated protein kinase signaling. This protein may play a role in alveoli branching during lung development as shown by a similar mouse protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: MGC23039, hSPRY2
Protein Interaction Partner: PTGER3, PRKAB2, KRTAP4-11, ATRIP, KRTAP5-6, KRTAP10-3, KRTAP10-8, KRTAP10-5, KRTAP10-11, KRTAP10-1, KRTAP10-9, LCE3E, KRTAP5-9, GP9, OTX1, MLLT6, MEOX2, MDFI, LASP1, LCE2D, LCE1B, RUNX1T1, AQP1, LCE3C, LCE4A, ZNF417, HEXIM2, CATSPER1, LONRF1, KRTAP4-7, KR
Protein Size: 315

分子量

35 kDa

基因ID

10253

NCBI登录号

NM_005842, NP_005833

UniProt

O43597

途径

EGFR Signaling Pathway, Sensory Perception of Sound, EGFR Downregulation