TMEM123 抗体 (C-Term)
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北京 101111
Quick Overview for TMEM123 抗体 (C-Term) (ABIN2784103)
抗原
See all TMEM123 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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原理
- TMEM123 Antibody - C-terminal region
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序列
- SSVTITTTMH SEAKKGSKFD TGSFVGGIVL TLGVLSILYI GCKMYYSRRG
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预测反应
- Human: 100%
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产品特性
- This is a rabbit polyclonal antibody against TMEM123. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human TMEM123
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anti-Transmembrane Protein 123 (TMEM123) (AA 34-133) antibody
TMEM123 适用: 人 WB 宿主: 小鼠 Monoclonal 1F4 unconjugated
anti-Transmembrane Protein 123 (TMEM123) (C-Term) antibodyTMEM123 适用: 人, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Transmembrane Protein 123 (TMEM123) (C-Term) antibodyTMEM123 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Transmembrane Protein 123 (TMEM123) (AA 1-208) antibodyTMEM123 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP50227-100UG
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- TMEM123 (Transmembrane Protein 123 (TMEM123))
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别名
- TMEM123
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背景
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Background Information: TMEM123 is a highly glycosylated transmembrane protein with a high content of threonine and serine residues in its extracellular domain, similar to a broadly defined category of proteins termed mucins. Exposure of some cell types to anti-PORIMIN (pro-oncosis receptor inducing membrane injury) antibody, crosslinks this protein on the cell surface and induces a type of cell death termed oncosis. Oncosis is distinct from apoptosis and is characterized by a loss of cell membrane integrity without DNA fragmentation. TMEM123 is proposed to function as a cell surface receptor that mediates cell death.This gene encodes a highly glycosylated transmembrane protein with a high content of threonine and serine residues in its extracellular domain, similar to a broadly defined category of proteins termed mucins. Exposure of some cell types to anti-PORIMIN (pro-oncosis receptor inducing membrane injury) antibody, crosslinks this protein on the cell surface and induces a type of cell death termed oncosis. Oncosis is distinct from apoptosis and is characterized by a loss of cell membrane integrity without DNA fragmentation. This gene product is proposed to function as a cell surface receptor that mediates cell death.
Gene Name: Transmembrane protein 123
Alternative Symbols: KCT3, PORMIN, PORIMIN
Protein Name: Porimin
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分子量
- 19kDa
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基因ID
- 114908
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NCBI登录号
- NP_443164
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UniProt
- Q8N131
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途径
- Regulation of Cell Size
抗原
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