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- 抗原 See all TMEM123 抗体
- TMEM123 (Transmembrane Protein 123 (TMEM123))
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抗原表位
- C-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This TMEM123 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- SSVTITTTMH SEAKKGSKFD TGSFVGGIVL TLGVLSILYI GCKMYYSRRG
- 预测反应
- Human: 100%
- 产品特性
- This is a rabbit polyclonal antibody against TMEM123. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human TMEM123
- Top Product
- Discover our top product TMEM123 Primary Antibody
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anti-Transmembrane Protein 123 (TMEM123) (AA 34-133) antibody
TMEM123 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1F4 unconjugated
anti-Transmembrane Protein 123 (TMEM123) (AA 173-188) antibodyTMEM123 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Transmembrane Protein 123 (TMEM123) antibodyTMEM123 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Transmembrane Protein 123 (TMEM123) (AA 1-208) antibodyTMEM123 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Transmembrane Protein 123 (TMEM123) (C-Term) antibodyTMEM123 适用: 人, 猴 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 208 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- TMEM123 (Transmembrane Protein 123 (TMEM123))
- 别名
- TMEM123 (TMEM123 产品)
- 别名
- KCT3 antibody, PORIMIN antibody, PORMIN antibody, 2310075C12Rik antibody, RGD1305625 antibody, kct3 antibody, pormin antibody, porimin antibody, transmembrane protein 123 antibody, transmembrane protein 123 L homeolog antibody, TMEM123 antibody, Tmem123 antibody, tmem123.L antibody, tmem123 antibody
- 背景
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TMEM123 is a highly glycosylated transmembrane protein with a high content of threonine and serine residues in its extracellular domain, similar to a broadly defined category of proteins termed mucins. Exposure of some cell types to anti-PORIMIN (pro-oncosis receptor inducing membrane injury) antibody, crosslinks this protein on the cell surface and induces a type of cell death termed oncosis. Oncosis is distinct from apoptosis and is characterized by a loss of cell membrane integrity without DNA fragmentation. TMEM123 is proposed to function as a cell surface receptor that mediates cell death.This gene encodes a highly glycosylated transmembrane protein with a high content of threonine and serine residues in its extracellular domain, similar to a broadly defined category of proteins termed mucins. Exposure of some cell types to anti-PORIMIN (pro-oncosis receptor inducing membrane injury) antibody, crosslinks this protein on the cell surface and induces a type of cell death termed oncosis. Oncosis is distinct from apoptosis and is characterized by a loss of cell membrane integrity without DNA fragmentation. This gene product is proposed to function as a cell surface receptor that mediates cell death.
Alias Symbols: KCT3, PORIMIN, PORMIN
Protein Interaction Partner: MAGEA11, ELAVL1,
Protein Size: 208 - 分子量
- 19 kDa
- 基因ID
- 114908
- NCBI登录号
- NM_052932, NP_443164
- UniProt
- Q8N131
- 途径
- Regulation of Cell Size
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