ANTXR1 抗体 (Middle Region)
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北京 101111
Quick Overview for ANTXR1 抗体 (Middle Region) (ABIN2784026)
抗原
See all ANTXR1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- VRWGEKGSTE EGAKLEKAKN ARVKMPEQEY EFPEPRNLNN NMRRPSSPRK
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
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产品特性
- This is a rabbit polyclonal antibody against ANTXR1. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human ANTXR1
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anti-anthrax Toxin Receptor 1 (ANTXR1) (C-Term) antibody
Verified ANTXR1 适用: 人 ELISA, IF 宿主: 山羊 Polyclonal unconjugated
anti-anthrax Toxin Receptor 1 (ANTXR1) (Internal Region) antibodyANTXR1 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-anthrax Toxin Receptor 1 (ANTXR1) (AA 315-564) antibodyANTXR1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-anthrax Toxin Receptor 1 (ANTXR1) (AA 481-497) antibodyANTXR1 适用: 人, 犬, 兔, 猴 WB 宿主: 小鼠 Monoclonal 200C1339(SB20) unconjugated
anti-anthrax Toxin Receptor 1 (ANTXR1) (AA 396-445) antibodyANTXR1 适用: 人, 小鼠, 大鼠, 犬, 兔, Cow, 豚鼠, 马, 猴, Bat, 小鸡, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-anthrax Toxin Receptor 1 (ANTXR1) (C-Term) antibodyANTXR1 适用: 人, 小鼠, 大鼠 WB, ICC 宿主: 兔 Polyclonal unconjugated
anti-anthrax Toxin Receptor 1 (ANTXR1) (AA 358-386) antibodyANTXR1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB15324 unconjugated
anti-anthrax Toxin Receptor 1 (ANTXR1) (Intermediate Domain) antibodyANTXR1 适用: 人, 小鼠, 大鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-anthrax Toxin Receptor 1 (ANTXR1) (C-Term) antibodyANTXR1 适用: 人, 小鼠, 大鼠 WB, IF, EIA 宿主: 兔 Polyclonal unconjugated
anti-anthrax Toxin Receptor 1 (ANTXR1) (AA 365-394), (Tyr382) antibodyANTXR1 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 564 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- ANTXR1 (anthrax Toxin Receptor 1 (ANTXR1))
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别名
- ANTXR1
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背景
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ANTXR1 is a type I transmembrane protein and is a tumor-specific endothelial marker that has been implicated in colorectal cancer. ANTXR1 has been shown to also be a docking protein or receptor for Bacillus anthracis toxin, the causative agent of the disease, anthrax. The binding of the protective antigen (PA) component, of the tripartite anthrax toxin, to this receptor protein mediates delivery of toxin components to the cytosol of cells. Once inside the cell, the other two components of anthrax toxin, edema factor (EF) and lethal factor (LF) disrupt normal cellular processes.The protein encoded by this gene is a type I transmembrane protein and is a tumor-specific endothelial marker that has been implicated in colorectal cancer. This protein has been shown to also be a docking protein or receptor for Bacillus anthracis toxin, the causative agent of the disease, anthrax. The binding of the protective antigen (PA) component, of the tripartite anthrax toxin, to this receptor protein mediates delivery of toxin components to the cytosol of cells. Once inside the cell, the other two components of anthrax toxin, edema factor (EF) and lethal factor (LF) disrupt normal cellular processes. Three alternatively spliced variants have been described.
Alias Symbols: ATR, FLJ10601, FLJ11298, FLJ21776, TEM8
Protein Interaction Partner: UBC, ELAVL1, Mad2l1, HDAC2, LRP6, BCL2L1,
Protein Size: 564 -
分子量
- 60 kDa
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基因ID
- 84168
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NCBI登录号
- NM_032208, NP_115584
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UniProt
- Q9H6X2
抗原
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