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PCDHA6 抗体 (C-Term)

This anti-PCDHA6 antibody is a 兔 多克隆 antibody detecting PCDHA6 in WB. Suitable for 人, 大鼠, 小鼠, 豚鼠, 马, Cow 和 犬.
产品编号 ABIN2784011
发货至: 中国

Quick Overview for PCDHA6 抗体 (C-Term) (ABIN2784011)

抗原

See all PCDHA6 抗体
PCDHA6 (Protocadherin alpha 6 (PCDHA6))

适用

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人, 大鼠, 小鼠, 豚鼠, 马, Cow, 犬

宿主

  • 42
  • 6

克隆类型

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  • 4
多克隆

标记

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This PCDHA6 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    C-Term

    序列

    LVKDHGEPAL TATATVLVSL VESGQAPKAS SRASVGAAGP EAALVDVNVY

    预测反应

    Cow: 86%, Dog: 86%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rat: 100%

    产品特性

    This is a rabbit polyclonal antibody against PCDHA6. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the C terminal region of human PCDHA6
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 803 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    PCDHA6 (Protocadherin alpha 6 (PCDHA6))

    别名

    PCDHA6

    背景

    PCDHA6 contains 6 cadherin domains. It is a potential calcium-dependent cell-adhesion protein. PCDHA6 may be involved in the establishment and maintenance of specific neuronal connections in the brain.This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined.
    Alias Symbols: CNR2, CNRN2, CNRS2, CRNR2, PCDH-ALPHA6
    Protein Interaction Partner: CUL3, UBC, RELN,
    Protein Size: 803

    分子量

    84 kDa

    基因ID

    56142

    NCBI登录号

    NM_031848, NP_114036
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