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GNPTAB 抗体 (N-Term)

GNPTAB 适用: 人, Cow, 犬, 豚鼠, 马, 小鼠, 兔, 大鼠, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2783922
发货至: 中国
  • 抗原 See all GNPTAB 抗体
    GNPTAB (N-Acetylglucosamine-1-Phosphate Transferase, alpha and beta Subunits (GNPTAB))
    抗原表位
    • 15
    • 15
    • 1
    • 1
    N-Term
    适用
    • 32
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, Cow, 犬, 豚鼠, 马, 小鼠, 兔, 大鼠, 斑马鱼
    宿主
    • 32
    克隆类型
    • 32
    多克隆
    标记
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This GNPTAB antibody is un-conjugated
    应用范围
    • 26
    • 26
    • 17
    • 6
    • 6
    • 6
    • 2
    Western Blotting (WB)
    序列
    FQFGEVVLEW SRDQYHVLFD SYRDNIAGKS FQNRLCLPMP IDVVYTWVNG
    预测反应
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
    产品特性
    This is a rabbit polyclonal antibody against GNPTAB. It was validated on Western Blot.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the N terminal region of human GNPTAB
    Top Product
    Discover our top product GNPTAB Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 1256 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    GNPTAB (N-Acetylglucosamine-1-Phosphate Transferase, alpha and beta Subunits (GNPTAB))
    别名
    GNPTAB (GNPTAB 产品)
    别名
    si:ch211-234f20.3 antibody, wu:fd55d09 antibody, zgc:122985 antibody, zgc:158502 antibody, GNPTA antibody, ICD antibody, EG432486 antibody, mKIAA1208 antibody, RGD1564821 antibody, N-acetylglucosamine-1-phosphate transferase alpha and beta subunits antibody, N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits antibody, N-acetylglucosamine-1-phosphotransferase subunits alpha/beta antibody, GNPTAB antibody, gnptab antibody, LOC100175423 antibody, Gnptab antibody
    背景
    This gene encodes two of three subunit types of the membrane-bound enzyme N-acetylglucosamine-1-phosphotransferase, a heterohexameric complex composed of two alpha, two beta, and two gamma subunits. The encoded protein is proteolytically cleaved at the Lys928-Asp929 bond to yield mature alpha and beta polypeptides while the gamma subunits are the product of a distinct gene (GeneID 84572). In the Golgi apparatus, the heterohexameric complex catalyzes the first step in the synthesis of mannose 6-phosphate recognition markers on certain oligosaccharides of newly synthesized lysosomal enzymes. These recognition markers are essential for appropriate trafficking of lysosomal enzymes. Mutations in this gene have been associated with both mucolipidosis II and mucolipidosis IIIA.
    Alias Symbols: DKFZp762B226, GNPTA, ICD, KIAA1208, MGC4170
    Protein Interaction Partner: AEN, ZNF250, STAMBPL1, FAM90A1, PSMA1, MAPK1, APP, UBC, DISC1,
    Protein Size: 1256
    分子量
    143 kDa
    基因ID
    79158
    NCBI登录号
    NM_024312, NP_077288
    UniProt
    Q3T906
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