GNPTAB 抗体 (N-Term)
Quick Overview for GNPTAB 抗体 (N-Term) (ABIN2783922)
抗原
See all GNPTAB 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- FQFGEVVLEW SRDQYHVLFD SYRDNIAGKS FQNRLCLPMP IDVVYTWVNG
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
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产品特性
- This is a rabbit polyclonal antibody against GNPTAB. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human GNPTAB
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anti-N-Acetylglucosamine-1-Phosphate Transferase, alpha and beta Subunits (GNPTAB) (AA 35-84) antibody
GNPTAB 适用: 人, Cow, 犬, 豚鼠, 马, 小鼠, 兔, 大鼠, 斑马鱼, Bat, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-N-Acetylglucosamine-1-Phosphate Transferase, alpha and beta Subunits (GNPTAB) (AA 42-350) antibodyGNPTAB 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-N-Acetylglucosamine-1-Phosphate Transferase, alpha and beta Subunits (GNPTAB) (N-Term) antibodyGNPTAB 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 1256 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- GNPTAB (N-Acetylglucosamine-1-Phosphate Transferase, alpha and beta Subunits (GNPTAB))
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别名
- GNPTAB
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背景
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This gene encodes two of three subunit types of the membrane-bound enzyme N-acetylglucosamine-1-phosphotransferase, a heterohexameric complex composed of two alpha, two beta, and two gamma subunits. The encoded protein is proteolytically cleaved at the Lys928-Asp929 bond to yield mature alpha and beta polypeptides while the gamma subunits are the product of a distinct gene (GeneID 84572). In the Golgi apparatus, the heterohexameric complex catalyzes the first step in the synthesis of mannose 6-phosphate recognition markers on certain oligosaccharides of newly synthesized lysosomal enzymes. These recognition markers are essential for appropriate trafficking of lysosomal enzymes. Mutations in this gene have been associated with both mucolipidosis II and mucolipidosis IIIA.
Alias Symbols: DKFZp762B226, GNPTA, ICD, KIAA1208, MGC4170
Protein Interaction Partner: AEN, ZNF250, STAMBPL1, FAM90A1, PSMA1, MAPK1, APP, UBC, DISC1,
Protein Size: 1256 -
分子量
- 143 kDa
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基因ID
- 79158
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NCBI登录号
- NM_024312, NP_077288
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UniProt
- Q3T906
抗原
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