ZP4 抗体 (N-Term)
Quick Overview for ZP4 抗体 (N-Term) (ABIN2783828)
抗原
See all ZP4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- MWLLRCVLLC VSLSLAVSGQ HKPEAPDYSS VLHCGPWSFQ FAVNLNQEAT
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预测反应
- Human: 100%
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产品特性
- This is a rabbit polyclonal antibody against ZP4. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human ZP4
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anti-Zona Pellucida Glycoprotein 4 (ZP4) (Internal Region) antibody
ZP4 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Zona Pellucida Glycoprotein 4 (ZP4) (AA 445-474), (C-Term) antibodyZP4 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB32332 unconjugated
anti-Zona Pellucida Glycoprotein 4 (ZP4) (AA 368-457) antibodyZP4 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Zona Pellucida Glycoprotein 4 (ZP4) (N-Term) antibodyZP4 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Zona Pellucida Glycoprotein 4 (ZP4) (N-Term) antibodyZP4 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 540 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- ZP4 (Zona Pellucida Glycoprotein 4 (ZP4))
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别名
- ZP4
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背景
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The zona pellucida is an extracellular matrix that surrounds the oocyte and early embryo. It is composed primarily of three or four glycoproteins with various functions during fertilization and preimplantation development. It is hypothesized that furin cleavage results in release of the mature protein from the plasma membrane for subsequent incorporation into the zona pellucida matrix.The zona pellucida is an extracellular matrix that surrounds the oocyte and early embryo. It is composed primarily of three or four glycoproteins with various functions during fertilization and preimplantation development. The nascent protein contains a N-terminal signal peptide sequence, a conserved ZP domain, a consensus furin cleavage site, and a C-terminal transmembrane domain. It is hypothesized that furin cleavage results in release of the mature protein from the plasma membrane for subsequent incorporation into the zona pellucida matrix. However, the requirement for furin cleavage in this process remains controversial based on mouse studies. Previously, this gene has been referred to as ZP1 or ZPB and thought to have similar functions as mouse Zp1. However, a human gene with higher similarity and chromosomal synteny to mouse Zp1 has been assigned the symbol ZP1 and this gene has been assigned the symbol ZP4. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: ZBP, ZP1, ZPB, Zp-4
Protein Interaction Partner: FURIN,
Protein Size: 540 -
分子量
- 49 kDa
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基因ID
- 57829
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NCBI登录号
- NM_021186, NP_067009
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UniProt
- Q12836
抗原
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