Neuroligin 4 抗体 (N-Term)
Quick Overview for Neuroligin 4 抗体 (N-Term) (ABIN2783800)
抗原
See all Neuroligin 4 (NLGN4) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- SILASYGNVI VITINYRLGI LGFLSTGDQA AKGNYGLLDQ IQALRWIEEN
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
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产品特性
- This is a rabbit polyclonal antibody against NLGN4X. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human NLGN4X
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 816 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Neuroligin 4 (NLGN4)
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别名
- NLGN4X
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背景
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NLGN4X is a member of a family of neuronal cell surface proteins. Members of this family may act as splice site-specific ligands for beta-neurexins and may be involved in the formation and remodeling of central nervous system synapses. It interacts with discs, large (Drosophila) homolog 4 (DLG4). NLGN4X might play a role in the autism and Asperger syndrome.Western blots using two different antibodies against two unique regions of this protein target confirm the same apparent molecular weight in our tests. This gene encodes a member of a family of neuronal cell surface proteins. Members of this family may act as splice site-specific ligands for beta-neurexins and may be involved in the formation and remodeling of central nervous system synapses. The encoded protein interacts with discs, large (Drosophila) homolog 4 (DLG4). Mutations in this gene have been associated with autism and Asperger syndrome. Two transcript variants encoding the same protein have been identified for this gene.
Alias Symbols: ASPGX2, AUTSX2, HLNX, HNLX, KIAA1260, MGC22376, NLGN, NLGN4, HNL4X
Protein Interaction Partner: DLGAP2, DLG4,
Protein Size: 816 -
分子量
- 92 kDa
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基因ID
- 57502
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NCBI登录号
- NM_020742, NP_065793
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UniProt
- Q8NFZ3
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途径
- Cell-Cell Junction Organization, Synaptic Membrane
抗原
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