Protocadherin gamma Subfamily A, 4 (PCDHGA4) (N-Term) 抗体
Quick Overview for Protocadherin gamma Subfamily A, 4 (PCDHGA4) (N-Term) 抗体 (ABIN2783724)
抗原
See all Protocadherin gamma Subfamily A, 4 (PCDHGA4) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- GDPVRSGTAR ILIILVDTND NAPVFTQPEY HVSVRENVPV GTRLLTVKAT
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预测反应
- Cow: 86%, Dog: 93%, Guinea Pig: 93%, Horse: 86%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 86%
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产品特性
- This is a rabbit polyclonal antibody against PCDHGA4. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human PCDHGA4
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anti-Protocadherin gamma Subfamily A, 4 (PCDHGA4) (AA 249-298) antibody
PCDHGA4 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Protocadherin gamma Subfamily A, 4 (PCDHGA4) (AA 1-931) antibodyPCDHGA4 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Protocadherin gamma Subfamily A, 4 (PCDHGA4) (N-Term) antibodyPCDHGA4 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Protocadherin gamma Subfamily A, 4 (PCDHGA4) antibodyPCDHGA4 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 820 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Protocadherin gamma Subfamily A, 4 (PCDHGA4)
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别名
- PCDHGA4
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背景
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PCDHGA4 is a single-pass type I membrane protein. It contains 6 cadherin domains. PCDHGA4 is a potential calcium-dependent cell-adhesion protein. It may be involved in the establishment and maintenance of specific neuronal connections in the brain.This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes.
Alias Symbols: PCDH-GAMMA-A4
Protein Size: 820 -
分子量
- 86 kDa
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基因ID
- 56111
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NCBI登录号
- NM_032053, NP_114442
抗原
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