PCDHA5 抗体 (N-Term)
Quick Overview for PCDHA5 抗体 (N-Term) (ABIN2783723)
抗原
See all PCDHA5 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- VYSRRGSLGS RLLLLWLLLA YWKAGSGQLH YSIPEEAKHG TFVGRIAQDL
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预测反应
- Cow: 86%, Dog: 79%, Guinea Pig: 93%, Horse: 86%, Human: 100%, Mouse: 100%, Rat: 100%
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产品特性
- This is a rabbit polyclonal antibody against PCDHA5. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human PCDHA5
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anti-Protocadherin alpha 5 (PCDHA5) (AA 183-289) antibody
PCDHA5 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1E8 unconjugated
anti-Protocadherin alpha 5 (PCDHA5) (N-Term) antibodyPCDHA5 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Protocadherin alpha 5 (PCDHA5) (N-Term) antibodyPCDHA5 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Protocadherin alpha 5 (PCDHA5) (AA 287-315) antibodyPCDHA5 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB31607 unconjugated
anti-Protocadherin alpha 5 (PCDHA5) (AA 294-323), (Middle Region) antibodyPCDHA5 适用: 人 WB, EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 936 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- PCDHA5 (Protocadherin alpha 5 (PCDHA5))
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别名
- PCDHA5
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背景
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The gene encoding PCDHA5 is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. PCDHA5 is a single-pass type I membrane protein. It contains 6 cadherin domains. PCDHA5 is a potential calcium-dependent cell-adhesion protein. It may be involved in the establishment and maintenance of specific neuronal connections in the brain.This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined.
Alias Symbols: CNR6, CNRN6, CNRS6, CRNR6, PCDH-ALPHA5
Protein Size: 936 -
分子量
- 99 kDa
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基因ID
- 56143
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NCBI登录号
- NM_018908, NP_061731
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UniProt
- Q9Y5H7
抗原
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