PCDHA11 抗体 (N-Term)
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北京 101111
Quick Overview for PCDHA11 抗体 (N-Term) (ABIN2783720)
抗原
See all PCDHA11 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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原理
- PCDHA11 Antibody - N-terminal region
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序列
- RLSKNEYFSL DSPTNGKQIK RLSLILKKSL DREKTPELNL LLTATDGGKP
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预测反应
- Cow: 93%, Guinea Pig: 77%, Horse: 92%, Human: 100%, Mouse: 93%, Pig: 85%, Rabbit: 86%, Rat: 91%
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产品特性
- This is a rabbit polyclonal antibody against PCDHA11. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP49346-100UG
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- PCDHA11 (Protocadherin alpha 11 (PCDHA11))
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别名
- PCDHA11
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背景
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Background Information: This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined.
Gene Name: Protocadherin alpha 11
Alternative Symbols: CNR7, CNRN7, CNRS7, CRNR7, PCDH-ALPHA11
Protein Name: Protocadherin alpha-11
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分子量
- 85kDa
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基因ID
- 56138
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NCBI登录号
- NP_114067
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UniProt
- Q9Y5I1
抗原
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