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SULF2 抗体 (C-Term)

This 兔 多克隆 antibody specifically detects SULF2 in WB 和 IHC. It exhibits reactivity toward 人, 小鼠, 大鼠, Cow, 犬, 马, 兔 和 Pig.It has been mentioned in 1 publication
产品编号 ABIN2783715
发货至: 中国
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Quick Overview for SULF2 抗体 (C-Term) (ABIN2783715)

抗原

See all SULF2 抗体
SULF2 (Sulfatase 2 (SULF2))

适用

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人, 小鼠, 大鼠, Cow, 犬, 马, 兔, Pig

宿主

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克隆类型

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多克隆

标记

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This SULF2 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

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    C-Term

    序列

    DVLNQLHVQL MELRSCKGYK QCNPRTRNMD LGLKDGGSYE QYRQFQRRKW

    预测反应

    Cow: 79%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 93%, Rabbit: 100%, Rat: 100%

    产品特性

    This is a rabbit polyclonal antibody against SULF2. It was validated on Western Blot and immunohistochemistry.

    纯化方法

    Protein A purified

    免疫原

    The immunogen is a synthetic peptide directed towards the C terminal region of human SULF2
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 870 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Uchimura, Morimoto-Tomita, Bistrup, Li, Lyon, Gallagher, Werb, Rosen: "HSulf-2, an extracellular endoglucosamine-6-sulfatase, selectively mobilizes heparin-bound growth factors and chemokines: effects on VEGF, FGF-1, and SDF-1." in: BMC biochemistry, Vol. 7, pp. 2, (2006) (PubMed).

  • 抗原

    SULF2 (Sulfatase 2 (SULF2))

    别名

    SULF2

    背景

    Heparan sulfate proteoglycans (HSPGs) act as coreceptors for numerous heparin-binding growth factors and cytokines and are involved in cell signaling. Heparan sulfate 6-O-endosulfatases, such as SULF2, selectively remove 6-O-sulfate groups from heparan sulfate. This activity modulates the effects of heparan sulfate by altering binding sites for signaling molecules.Heparan sulfate proteoglycans (HSPGs) act as coreceptors for numerous heparin-binding growth factors and cytokines and are involved in cell signaling. Heparan sulfate 6-O-endosulfatases, such as SULF2, selectively remove 6-O-sulfate groups from heparan sulfate. This activity modulates the effects of heparan sulfate by altering binding sites for signaling molecules (Dai et al., 2005 [PubMed 16192265]).[supplied by OMIM].
    Alias Symbols: DKFZp313E091, FLJ90554, HSULF-2, KIAA1247, MGC126411
    Protein Interaction Partner: MYC, UBC,
    Protein Size: 870

    分子量

    98 kDa

    基因ID

    55959

    NCBI登录号

    NM_018837, NP_061325

    UniProt

    Q8IWU5
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