SMPD3 抗体 (Middle Region)
(1 reference)Quick Overview for SMPD3 抗体 (Middle Region) (ABIN2783713)
抗原
See all SMPD3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- RPPEADDPVP GGQARNGAGG GPRGQTPNHN QQDGDSGSLG SPSASRESLV
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
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产品特性
- This is a rabbit polyclonal antibody against SMPD3. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human SMPD3
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anti-Sphingomyelin Phosphodiesterase 3 (SMPD3) (AA 1-655) antibody
SMPD3 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Sphingomyelin Phosphodiesterase 3 (SMPD3) (AA 401-655) antibodySMPD3 适用: 人 ELISA, IHC, IP 宿主: 兔 Polyclonal unconjugated
anti-Sphingomyelin Phosphodiesterase 3 (SMPD3) (AA 1-655) antibodySMPD3 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Sphingomyelin Phosphodiesterase 3 (SMPD3) (AA 416-655) antibodySMPD3 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Sphingomyelin Phosphodiesterase 3 (SMPD3) antibodySMPD3 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Sphingomyelin Phosphodiesterase 3 (SMPD3) antibodySMPD3 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 655 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "Analysis of membrane topology of neutral sphingomyelinase 2." in: FEBS letters, Vol. 581, Issue 7, pp. 1323-8, (2007) (PubMed).
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: "Analysis of membrane topology of neutral sphingomyelinase 2." in: FEBS letters, Vol. 581, Issue 7, pp. 1323-8, (2007) (PubMed).
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- SMPD3 (Sphingomyelin Phosphodiesterase 3 (SMPD3))
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别名
- SMPD3
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背景
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SMPD3 catalyzes the hydrolysis of sphingomyelin to form ceramide and phosphocholine. Ceramide mediates numerous cellular functions, such as apoptosis and growth arrest, and is capable of regulating these 2 cellular events independently. Also hydrolyzes sphingosylphosphocholine. SMPD3 regulates the cell cycle by acting as a growth suppressor in confluent cells. It probably acts as a regulator of postnatal development and participates in bone and dentin mineralization.
Alias Symbols: FLJ22593, MGC138443, NSMASE2
Protein Size: 655 -
分子量
- 71 kDa
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基因ID
- 55512
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NCBI登录号
- NM_018667, NP_061137
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UniProt
- Q9NY59
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途径
- Hormone Transport
抗原
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