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B3GALTL 抗体 (Middle Region)

This 兔 多克隆 anti-B3GALTL antibody specifically detects B3GALTL in WB. The antibody is reactive with 人, 小鼠, 犬 和 大鼠 samples.
产品编号 ABIN2783666
发货至: 中国
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Quick Overview for B3GALTL 抗体 (Middle Region) (ABIN2783666)

抗原

See all B3GALTL 抗体
B3GALTL (beta 1,3-Galactosyltransferase-Like (B3GALTL))

适用

人, 小鼠, 犬, 大鼠

宿主

  • 12
  • 1

克隆类型

  • 13
多克隆

标记

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This B3GALTL antibody is un-conjugated

应用范围

  • 6
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  • 1
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Western Blotting (WB)
  • 抗原表位

    • 2
    • 1
    • 1
    Middle Region

    序列

    DYPKDYLSHQ VPISFHKHWN IDPVKVYFTW LAPSDEDKAR QETQKGFREE

    预测反应

    Dog: 93%, Human: 100%, Mouse: 79%, Rat: 79%

    产品特性

    This is a rabbit polyclonal antibody against B3GALTL. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the middle region of human B3GALTL
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 498 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    B3GALTL (beta 1,3-Galactosyltransferase-Like (B3GALTL))

    别名

    B3GALTL

    背景

    B3GALTL is the O-fucosyltransferase that transfers glucose toward fucose with a beta-1,3 linkage. B3GALTL specifically glucosylates O-linked fucosylglycan on TSP type-1 domains of proteins, thereby contributing to elongation of O-fucosylglycan.B3GALTL is a beta-1,3-glucosyltransferase involved in the synthesis of the unusual O-linked disaccharide glucosyl-beta-1,3-fucose-O- found on the thrombospondin (see THBS1, MIM 188060) type-1 repeats (TSRs) of many biologically important proteins. Biosynthesis of glucosyl-beta-1,3-fucose-O- is initiated by protein O-fucosyltransferase-2 (POFUT2, MIM 610249), which attaches the fucosyl residue to a serine or threonine within the TSR. B3GALTL subsequently transfers the glucose onto TSR-fucose (Hess et al., 2008 [PubMed 18199743]).[supplied by OMIM]. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-270 DN999521.1 41-310 271-457 AB101481.1 161-347 458-467 DN999521.1 499-508 468-1217 AB101481.1 358-1107 1218-1279 DA290408.1 515-576 1280-1607 AB101481.1 1170-1497 1608-2495 AY190526.1 1498-2385 2496-3459 AY190526.1 2387-3350 3460-4071 AV728071.1 87-698 4072-4221 AA769548.1 1-150 c
    Alias Symbols: B3GTL, B3Glc-T, Gal-T, beta3Glc-T, B3GLCT
    Protein Interaction Partner: UBC, ELAVL1,
    Protein Size: 498

    分子量

    56 kDa

    基因ID

    145173

    NCBI登录号

    NM_194318, NP_919299

    UniProt

    Q6Y288
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