NEK3 抗体 (N-Term)
Quick Overview for NEK3 抗体 (N-Term) (ABIN2783629)
抗原
See all NEK3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- FTQMCLGVNH IHKKRVLHRD IKSKNIFLTQ NGKVKLGDFG SARLLSNPMA
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预测反应
- Cow: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 93%, Yeast: 79%, Zebrafish: 86%
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产品特性
- This is a rabbit polyclonal antibody against NEK3. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human NEK3
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anti-NIMA related kinase 3 (NEK3) (AA 406-506) antibody
NEK3 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 2F8 unconjugated
anti-NIMA related kinase 3 (NEK3) (AA 267-506) antibodyNEK3 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-NIMA related kinase 3 (NEK3) (AA 1-506) antibodyNEK3 适用: 人 WB, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-NIMA related kinase 3 (NEK3) (AA 1-506) antibodyNEK3 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-NIMA related kinase 3 (NEK3) (AA 331-361) antibodyNEK3 适用: 人 WB 宿主: 兔 Polyclonal RB2961 unconjugated
anti-NIMA related kinase 3 (NEK3) (AA 108-157) antibodyNEK3 适用: 人, Cow, 豚鼠, 马, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-NIMA related kinase 3 (NEK3) (AA 446-474), (C-Term) antibodyNEK3 适用: 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB34647 unconjugated
anti-NIMA related kinase 3 (NEK3) antibodyNEK3 适用: 人 WB, IF, IC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 506 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- NEK3 (NIMA related kinase 3 (NEK3))
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别名
- NEK3
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背景
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NEK3 is a member of the NimA (never in mitosis A) family of serine/threonine protein kinases. It differs from other NimA family members in that it is not cell cycle regulated and is found primarily in the cytoplasm. The kinase is activated by prolactin stimulation, leading to phosphorylation of VAV2 guanine nucleotide exchange factor, paxillin, and activation of the RAC1 GTPase.In Aspergillus nidulans, lack of the serine/threonine kinase NimA (never in mitosis A) results in cell cycle arrest in G2, while overexpression causes the premature onset of mitotic events. The protein encoded by this gene is similar in sequence to the Aspergillus nidulans protein and may therefore play a role in mitotic regulation. However, the encoded protein differs from other NimA family members in that it is not cell cycle regulated and is found primarily in the cytoplasm. Three transcript variants have been found for this gene, but the full-length nature of only two of them has been characterized.
Alias Symbols: HSPK36, MGC29949
Protein Interaction Partner: HDAC6, NMNAT1, CDCA8, BPGM, VAV2, PRLR, VAV1, CSN2,
Protein Size: 506 -
分子量
- 58 kDa
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基因ID
- 4752
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NCBI登录号
- NM_002498, NP_002489
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UniProt
- P51956
抗原
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