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SHMT1 抗体 (N-Term)

This 兔 多克隆 anti-SHMT1 antibody specifically detects SHMT1 in WB. The antibody is reactive with 人, 小鼠, 大鼠, 犬, 豚鼠, 斑马鱼, 绵羊, 兔, Cow, 马 和 Saccharomyces cerevisiae samples.
产品编号 ABIN2783618
发货至: 中国
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Quick Overview for SHMT1 抗体 (N-Term) (ABIN2783618)

抗原

See all SHMT1 抗体
SHMT1 (serine Hydroxymethyltransferase 1 (Soluble) (SHMT1))

适用

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人, 小鼠, 大鼠, 犬, 豚鼠, 斑马鱼, 绵羊, 兔, Cow, 马, Saccharomyces cerevisiae

宿主

  • 37
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克隆类型

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多克隆

标记

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This SHMT1 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    N-Term

    序列

    NIIKKESNRQ RVGLELIASE NFASRAVLEA LGSCLNNKYS EGYPGQRYYG

    预测反应

    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Yeast: 100%, Zebrafish: 100%

    产品特性

    This is a rabbit polyclonal antibody against SHMT1. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N terminal region of human SHMT1
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 483 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    SHMT1 (serine Hydroxymethyltransferase 1 (Soluble) (SHMT1))

    别名

    SHMT1

    背景

    This gene encodes the cellular form of serine hydroxymethyltransferase, a pyridoxal phosphate-containing enzyme that catalyzes the reversible conversion of serine and tetrahydrofolate to glycine and 5,10-methylene tetrahydrofolate. This reaction provides one carbon units for synthesis of methionine, thymidylate, and purines in the cytoplasm. This gene is located within the Smith-Magenis syndrome region on chromosome 17. Alternative splicing of this gene results in 2 transcript variants encoding 2 different isoforms. Additional transcript variants have been described, but their biological validity has not been determined.
    Alias Symbols: CSHMT, MGC15229, MGC24556, SHMT
    Protein Interaction Partner: UBC, SULT1A3, SHMT1, MAPK9, C18orf25, FAM129B, SNX6, XPO5, VPS29, PBDC1, GSPT2, HIST1H4A, CARS, ATP6V1C1, APEH, CTTN, TTC1, TSN, STAT1, SNX2, SHMT2, PAWR, IDE, HARS, GTF2F2, GARS, DEDD, MCAT, ZC3H4, HSPA1L, SUMO1, SUMO2, SUMO3, PRSS23, PIM1, CSNK2B, DLEU1
    Protein Size: 483

    分子量

    53 kDa

    基因ID

    6470

    NCBI登录号

    NM_004169, NP_004160

    UniProt

    Q5RFK5
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