SHMT1 抗体 (N-Term)
Quick Overview for SHMT1 抗体 (N-Term) (ABIN2783618)
抗原
See all SHMT1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- NIIKKESNRQ RVGLELIASE NFASRAVLEA LGSCLNNKYS EGYPGQRYYG
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Yeast: 100%, Zebrafish: 100%
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产品特性
- This is a rabbit polyclonal antibody against SHMT1. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human SHMT1
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 483 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- SHMT1 (serine Hydroxymethyltransferase 1 (Soluble) (SHMT1))
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别名
- SHMT1
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背景
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This gene encodes the cellular form of serine hydroxymethyltransferase, a pyridoxal phosphate-containing enzyme that catalyzes the reversible conversion of serine and tetrahydrofolate to glycine and 5,10-methylene tetrahydrofolate. This reaction provides one carbon units for synthesis of methionine, thymidylate, and purines in the cytoplasm. This gene is located within the Smith-Magenis syndrome region on chromosome 17. Alternative splicing of this gene results in 2 transcript variants encoding 2 different isoforms. Additional transcript variants have been described, but their biological validity has not been determined.
Alias Symbols: CSHMT, MGC15229, MGC24556, SHMT
Protein Interaction Partner: UBC, SULT1A3, SHMT1, MAPK9, C18orf25, FAM129B, SNX6, XPO5, VPS29, PBDC1, GSPT2, HIST1H4A, CARS, ATP6V1C1, APEH, CTTN, TTC1, TSN, STAT1, SNX2, SHMT2, PAWR, IDE, HARS, GTF2F2, GARS, DEDD, MCAT, ZC3H4, HSPA1L, SUMO1, SUMO2, SUMO3, PRSS23, PIM1, CSNK2B, DLEU1
Protein Size: 483 -
分子量
- 53 kDa
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基因ID
- 6470
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NCBI登录号
- NM_004169, NP_004160
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UniProt
- Q5RFK5
抗原
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