TTC5 抗体 (C-Term)
Quick Overview for TTC5 抗体 (C-Term) (ABIN2783601)
抗原
See all TTC5 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- GDSVAIPEPN LRLHRIQHKG KDYSFSSVRV ETPLLLVVNG KPQGSSSQAV
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预测反应
- Cow: 100%, Dog: 86%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 86%, Pig: 100%, Rabbit: 86%, Rat: 93%
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产品特性
- This is a rabbit polyclonal antibody against TTC5. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human TTC5
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 440 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- TTC5 (Tetratricopeptide Repeat Domain 5 (TTC5))
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别名
- TTC5
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背景
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TTC5 is an adapter protein involved in p53/TP53 response that acts by regulating and mediating the assembly of multi-protein complexes. It is required to facilitate the interaction between JMY and p300/EP300 and increase p53/TP53-dependent transcription and apoptosis. It prevents p53/TP53 degradation by MDM2.
Alias Symbols: Strap
Protein Interaction Partner: AR, NR3C1, ESR1, CAMK2D, CAMK2B, UBC, CAND1, COPS5, CUL3, ELAVL1,
Protein Size: 440 -
分子量
- 49 kDa
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基因ID
- 91875
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NCBI登录号
- NM_138376, NP_612385
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UniProt
- Q8N0Z6
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途径
- Chromatin Binding
抗原
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