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CHST14 抗体 (Middle Region)

CHST14 适用: 人, 小鼠, 大鼠, Pig, Cow, 犬, 豚鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2783597
发货至: 中国
  • 抗原 See all CHST14 抗体
    CHST14 (Carbohydrate (N-Acetylgalactosamine 4-0) Sulfotransferase 14 (CHST14))
    抗原表位
    • 8
    • 7
    • 6
    • 6
    • 4
    • 1
    Middle Region
    适用
    • 24
    • 21
    • 10
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠, Pig, Cow, 犬, 豚鼠
    宿主
    • 28
    克隆类型
    • 28
    多克隆
    标记
    • 8
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CHST14 antibody is un-conjugated
    应用范围
    • 18
    • 17
    • 3
    • 1
    • 1
    Western Blotting (WB)
    序列
    REYQQRYGAE IVRRYRAGAG PSPAGDDVTF PEFLRYLVDE DPERMNEHWM
    预测反应
    Cow: 100%, Dog: 100%, Guinea Pig: 86%, Human: 100%, Mouse: 100%, Pig: 100%, Rat: 100%
    产品特性
    This is a rabbit polyclonal antibody against CHST14. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the middle region of human CHST14
    Top Product
    Discover our top product CHST14 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 338 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Janecke, Li, Boehm, Krabichler, Rohrbach, Müller, Fuchs, Golas, Katagiri, Ziegler, Gahl, Wilnai, Zoppi, Geller, Giunta, Slavotinek, Steinmann: "The phenotype of the musculocontractural type of Ehlers-Danlos syndrome due to CHST14 mutations." in: American journal of medical genetics. Part A, Vol. 170A, Issue 1, pp. 103-15, (2016) (PubMed).

  • 抗原
    CHST14 (Carbohydrate (N-Acetylgalactosamine 4-0) Sulfotransferase 14 (CHST14))
    别名
    CHST14 (CHST14 产品)
    别名
    ATCS antibody, D4ST1 antibody, HNK1ST antibody, 2600016L03Rik antibody, D4ST-1 antibody, D4st1 antibody, d4st1 antibody, MGC136487 antibody, wu:fc04a01 antibody, zgc:136487 antibody, carbohydrate sulfotransferase 14 antibody, carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 14 antibody, CHST14 antibody, Chst14 antibody, chst14 antibody
    背景
    CHST14 belongs to the sulfotransferase 2 family. CHST14 catalyzes the transfer of sulfate to position 4 of the N-acetylgalactosamine (GalNAc) residue of dermatan sulfate. It transfers sulfate to the C-4 hydroxyl of beta1,4-linked GalNAc that is substituted with an alpha-linked iduronic acid (IdoUA) at the C-3 hydroxyl. It transfers sulfate more efficiently to GalNAc residues in -IdoUA-GalNAc-IdoUA- than in -GlcUA-GalNAc-GlcUA-sequences. CHST14 has preference for partially desulfated dermatan sulfate. Addition of sulfate to GalNAc may occur immediately after epimerization of GlcUA to IdoUA.
    Alias Symbols: D4ST-1, D4ST1, HD4ST, HNK1ST, ATCS
    Protein Interaction Partner: UBD,
    Protein Size: 338
    分子量
    35 kDa
    基因ID
    113189
    UniProt
    Q8NCH0
    途径
    Glycosaminoglycan Metabolic Process
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