ALG2 抗体 (C-Term)
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北京 101111
Quick Overview for ALG2 抗体 (C-Term) (ABIN2783587)
抗原
See all ALG2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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原理
- ALG2 Antibody - C-terminal region
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序列
- QSDLGQYVTF LRSFSDKQKI SLLHSCTCVL YTPSNEHFGI VPLEAMYMQC
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预测反应
- Cow: 100%, Dog: 93%, Goat: 86%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 100%, Zebrafish: 93%
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产品特性
- This is a rabbit polyclonal antibody against ALG2. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human ALG2
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anti-Asparagine-Linked Glycosylation 2, alpha-1,3-Mannosyltransferase Homolog (ALG2) (AA 303-405) antibody
ALG2 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Asparagine-Linked Glycosylation 2, alpha-1,3-Mannosyltransferase Homolog (ALG2) (AA 1-416) antibodyALG2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Asparagine-Linked Glycosylation 2, alpha-1,3-Mannosyltransferase Homolog (ALG2) antibodyALG2 适用: 人, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Asparagine-Linked Glycosylation 2, alpha-1,3-Mannosyltransferase Homolog (ALG2) (AA 197-416) antibodyALG2 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Asparagine-Linked Glycosylation 2, alpha-1,3-Mannosyltransferase Homolog (ALG2) antibodyKD Validated ALG2 适用: 人 WB 宿主: 小鼠 Monoclonal 25GB3760 unconjugated
anti-Asparagine-Linked Glycosylation 2, alpha-1,3-Mannosyltransferase Homolog (ALG2) antibodyALG2 适用: 人, 小鼠, 大鼠 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Asparagine-Linked Glycosylation 2, alpha-1,3-Mannosyltransferase Homolog (ALG2) (AA 254-282) antibodyALG2 适用: 人 WB 宿主: 兔 Polyclonal RB36980 unconjugated
anti-Asparagine-Linked Glycosylation 2, alpha-1,3-Mannosyltransferase Homolog (ALG2) (AA 290-339) antibodyALG2 适用: 人, 小鼠, 大鼠, Cow, 豚鼠, 马, 兔, Saccharomyces cerevisiae, 小鸡, Hamster, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Asparagine-Linked Glycosylation 2, alpha-1,3-Mannosyltransferase Homolog (ALG2) antibodyALG2 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Asparagine-Linked Glycosylation 2, alpha-1,3-Mannosyltransferase Homolog (ALG2) (AA 1-416) antibodyALG2 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8095062
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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: "Congenital myasthenic syndromes due to mutations in ALG2 and ALG14." in: Brain : a journal of neurology, Vol. 136, Issue Pt 3, pp. 944-56, (2013) (PubMed).
: "A severe human metabolic disease caused by deficiency of the endoplasmatic mannosyltransferase hALG11 leads to congenital disorder of glycosylation-Ip." in: Human molecular genetics, Vol. 19, Issue 8, pp. 1413-24, (2010) (PubMed).
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- ALG2 (Asparagine-Linked Glycosylation 2, alpha-1,3-Mannosyltransferase Homolog (ALG2))
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别名
- ALG2
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背景
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Background Information: ALG2 is a member of the glycosyltransferase 1 family. It acts as an alpha 1,3 mannosyltransferase, mannosylating Man(2)GlcNAc(2)-dolichol diphosphate and Man(1)GlcNAc(2)-dolichol diphosphate to form Man(3)GlcNAc(2)-dolichol diphosphate. Defects in this gene have been associated with congenital disorder of glycosylation type Ih (CDG-Ii).This gene encodes a member of the glycosyltransferase 1 family. The encoded protein acts as an alpha 1,3 mannosyltransferase, mannosylating Man(2)GlcNAc(2)-dolichol diphosphate and Man(1)GlcNAc(2)-dolichol diphosphate to form Man(3)GlcNAc(2)-dolichol diphosphate. Defects in this gene have been associated with congenital disorder of glycosylation type Ih (CDG-Ii). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Gene Name: Asparagine-linked glycosylation 2, alpha-1,3-mannosyltransferase homolog (S. cerevisiae)
Alternative Symbols: CDG1I, CDGIi, CMS14, NET38, CMSTA3, hALPG2
Protein Name: Alpha-1,3/1,6-mannosyltransferase ALG2
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分子量
- 47kDa
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基因ID
- 85365
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NCBI登录号
- NP_149078
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UniProt
- Q9H553
抗原
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