ALG2 抗体 (C-Term)
(2 references)Quick Overview for ALG2 抗体 (C-Term) (ABIN2783587)
抗原
See all ALG2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- QSDLGQYVTF LRSFSDKQKI SLLHSCTCVL YTPSNEHFGI VPLEAMYMQC
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预测反应
- Cow: 100%, Dog: 93%, Goat: 86%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 100%, Zebrafish: 93%
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产品特性
- This is a rabbit polyclonal antibody against ALG2. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human ALG2
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anti-Asparagine-Linked Glycosylation 2, alpha-1,3-Mannosyltransferase Homolog (ALG2) (AA 303-405) antibody
ALG2 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Asparagine-Linked Glycosylation 2, alpha-1,3-Mannosyltransferase Homolog (ALG2) (AA 1-416) antibodyALG2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Asparagine-Linked Glycosylation 2, alpha-1,3-Mannosyltransferase Homolog (ALG2) (AA 197-416) antibodyALG2 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Asparagine-Linked Glycosylation 2, alpha-1,3-Mannosyltransferase Homolog (ALG2) antibodyALG2 适用: 人, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Asparagine-Linked Glycosylation 2, alpha-1,3-Mannosyltransferase Homolog (ALG2) antibodyALG2 适用: 人, 小鼠, 大鼠 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Asparagine-Linked Glycosylation 2, alpha-1,3-Mannosyltransferase Homolog (ALG2) (AA 1-416) antibodyALG2 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Asparagine-Linked Glycosylation 2, alpha-1,3-Mannosyltransferase Homolog (ALG2) (AA 290-339) antibodyALG2 适用: 人, 小鼠, 大鼠, Cow, 豚鼠, 马, 兔, Saccharomyces cerevisiae, Pig, 小鸡, Hamster, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Asparagine-Linked Glycosylation 2, alpha-1,3-Mannosyltransferase Homolog (ALG2) (AA 197-416) antibodyALG2 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Asparagine-Linked Glycosylation 2, alpha-1,3-Mannosyltransferase Homolog (ALG2) antibodyALG2 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 416 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "Congenital myasthenic syndromes due to mutations in ALG2 and ALG14." in: Brain : a journal of neurology, Vol. 136, Issue Pt 3, pp. 944-56, (2013) (PubMed).
: "A severe human metabolic disease caused by deficiency of the endoplasmatic mannosyltransferase hALG11 leads to congenital disorder of glycosylation-Ip." in: Human molecular genetics, Vol. 19, Issue 8, pp. 1413-24, (2010) (PubMed).
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: "Congenital myasthenic syndromes due to mutations in ALG2 and ALG14." in: Brain : a journal of neurology, Vol. 136, Issue Pt 3, pp. 944-56, (2013) (PubMed).
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- ALG2 (Asparagine-Linked Glycosylation 2, alpha-1,3-Mannosyltransferase Homolog (ALG2))
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别名
- ALG2
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背景
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ALG2 is a member of the glycosyltransferase 1 family. It acts as an alpha 1,3 mannosyltransferase, mannosylating Man(2)GlcNAc(2)-dolichol diphosphate and Man(1)GlcNAc(2)-dolichol diphosphate to form Man(3)GlcNAc(2)-dolichol diphosphate. Defects in this gene have been associated with congenital disorder of glycosylation type Ih (CDG-Ii).This gene encodes a member of the glycosyltransferase 1 family. The encoded protein acts as an alpha 1,3 mannosyltransferase, mannosylating Man(2)GlcNAc(2)-dolichol diphosphate and Man(1)GlcNAc(2)-dolichol diphosphate to form Man(3)GlcNAc(2)-dolichol diphosphate. Defects in this gene have been associated with congenital disorder of glycosylation type Ih (CDG-Ii). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: CDGIi, FLJ14511, hALPG2, NET38
Protein Interaction Partner: UBC, PLSCR3, SHISA5, PDCD6IP, ALG2, VPS28, PTPN23, SEC31A, TSG101, LAMP1, HSP90AA1, PTK2B, ANXA11, ANXA7, VPS37A, PEF1, SRI,
Protein Size: 416 -
分子量
- 47 kDa
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基因ID
- 85365
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NCBI登录号
- NM_033087, NP_149078
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UniProt
- Q9H553
抗原
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