POLR1B 抗体 (Middle Region)
Quick Overview for POLR1B 抗体 (Middle Region) (ABIN2783529)
抗原
See all POLR1B 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- SDKFQVRTTG ARDRVTNQPI GGRNVQGGIR FGEMERDALL AHGTSFLLHD
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预测反应
- Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 86%, Pig: 100%, Rabbit: 100%, Rat: 93%, Zebrafish: 86%
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产品特性
- This is a rabbit polyclonal antibody against POLR1B. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human POLR1B
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 1135 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- POLR1B (Polymerase (RNA) I Polypeptide B, 128kDa (POLR1B))
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别名
- POLR1B
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背景
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Eukaryotic RNA polymerase I (pol I) is responsible for the transcription of ribosomal RNA (rRNA) genes and production of rRNA, the primary component of ribosomes. Pol I is a multisubunit enzyme composed of 6 to 14 polypeptides, depending on the species. Most of the mass of the pol I complex derives from the 2 largest subunits, Rpa1 and Rpa2 in yeast. POLR1B is homologous to Rpa2 (Seither and Grummt, 1996 [PubMed 8921381]).
Alias Symbols: FLJ10816, FLJ21921, MGC131780, RPA135, Rpo1-2, RPA2
Protein Interaction Partner: UBC, RPA3, RPA2, RPA1, RRN3, HDAC6, GIT2, MED20, NMI, LDB1, ZNF207, RPL37, CCND1, AKT2, ACTA1, ERBB2, ACTB, TSR1, POLR1D, POLR1A, CD3EAP, NOP56, POLR1C, DHX8, CAND1, ARRB2, LZTR1, TAF1D, USP11, POLR1E, EIF3L, NFKBIB, POLR1B, ESR1, RIBIN,
Protein Size: 1135 -
分子量
- 128 kDa
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基因ID
- 84172
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NCBI登录号
- NM_019014, NP_061887
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UniProt
- Q9H9Y6
抗原
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