CMAS 抗体 (N-Term)
Quick Overview for CMAS 抗体 (N-Term) (ABIN2783528)
抗原
See all CMAS 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- GRGVEKPPHL AALILARGGS KGIPLKNIKH LAGVPLIGWV LRAALDSGAF
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
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产品特性
- This is a rabbit polyclonal antibody against CMAS. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human CMAS
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 434 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- CMAS (Cytidine Monophosphate N-Acetylneuraminic Acid Synthetase (CMAS))
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别名
- CMAS
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背景
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CMAS is an enzyme that catalyzes the activation of Neu5Ac to Cytidine 5-prime-monophosphate N-acetylneuraminic acid (CMP-Neu5Ac), which provides the substrate required for the addition of sialic acid. Sialic acids of cell surface glycoproteins and glycolipids play a pivotal role in the structure and function of animal tissues. The pattern of cell surface sialylation is highly regulated during embryonic development, and changes with stages of differentiation. Studies of a similar murine protein suggest that this protein localizes to the nucleus.The enzyme encoded by this gene catalyzes the activation of Neu5Ac to Cytidine 5-prime-monophosphate N-acetylneuraminic acid (CMP-Neu5Ac), which provides the substrate required for the addition of sialic acid. Sialic acids of cell surface glycoproteins and glycolipids play a pivotal role in the structure and function of animal tissues. The pattern of cell surface sialylation is highly regulated during embryonic development, and changes with stages of differentiation. Studies of a similar murine protein suggest that this protein localizes to the nucleus.
Alias Symbols: CSS
Protein Interaction Partner: SUMO2, SUMO3, UBC, FBXO6, APP, SIGLEC12,
Protein Size: 434 -
分子量
- 48 kDa
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基因ID
- 55907
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NCBI登录号
- NM_018686, NP_061156
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UniProt
- Q8NFW8
抗原
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