POLR3B 抗体 (C-Term)
(1 reference)Quick Overview for POLR3B 抗体 (C-Term) (ABIN2783516)
抗原
See all POLR3B 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- IEKVMISSNA EDAFLIKMLL RQTRRPEIGD KFSSRHGQKG VCGLIVPQED
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预测反应
- Cow: 100%, Dog: 100%, Goat: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 93%, Zebrafish: 100%
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产品特性
- This is a rabbit polyclonal antibody against POLR3B. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human POLR3B
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anti-Polymerase (RNA) III (DNA Directed) Polypeptide B (POLR3B) (AA 2-100) antibody
POLR3B 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3G10 unconjugated
anti-Polymerase (RNA) III (DNA Directed) Polypeptide B (POLR3B) (AA 831-939) antibodyPOLR3B 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Polymerase (RNA) III (DNA Directed) Polypeptide B (POLR3B) (C-Term) antibodyPOLR3B 适用: 人, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Polymerase (RNA) III (DNA Directed) Polypeptide B (POLR3B) antibodyPOLR3B 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Polymerase (RNA) III (DNA Directed) Polypeptide B (POLR3B) (AA 866-915) antibodyPOLR3B 适用: 人, 小鼠, 大鼠, 犬, Cow, 兔, 斑马鱼, Pig, 马, 猴, 豚鼠, Drosophila melanogaster, 小鸡, Hamster, Bat, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-Polymerase (RNA) III (DNA Directed) Polypeptide B (POLR3B) (AA 680-900) antibodyPOLR3B 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Polymerase (RNA) III (DNA Directed) Polypeptide B (POLR3B) (C-Term) antibodyPOLR3B 适用: 人, 小鼠, 大鼠, Drosophila melanogaster WB 宿主: 兔 Polyclonal unconjugated
anti-Polymerase (RNA) III (DNA Directed) Polypeptide B (POLR3B) antibodyPOLR3B 适用: 人, 小鼠, 大鼠, 犬, Cow, 兔, 斑马鱼, Pig, 猴 WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 1133 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "Mutation of RNA Pol III subunit rpc2/polr3b Leads to Deficiency of Subunit Rpc11 and disrupts zebrafish digestive development." in: PLoS biology, Vol. 5, Issue 11, pp. e312, (2007) (PubMed).
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: "Mutation of RNA Pol III subunit rpc2/polr3b Leads to Deficiency of Subunit Rpc11 and disrupts zebrafish digestive development." in: PLoS biology, Vol. 5, Issue 11, pp. e312, (2007) (PubMed).
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- POLR3B (Polymerase (RNA) III (DNA Directed) Polypeptide B (POLR3B))
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别名
- POLR3B
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背景
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POLR3B belongs to the RNA polymerase beta chain family. DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. POLR3B is the second largest core component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. It is proposed to contribute to the polymerase catalytic activity and forms the polymerase active center together with the largest subunit. Pol III is composed of mobile elements and RPC2 is part of the core element with the central large cleft and probably a clamp element that moves to open and close the cleft.
Alias Symbols: FLJ10388, RPC2, C128, HLD8
Protein Interaction Partner: SUMO2, UBC, POLR3H, TSR1, POLR1D, CRCP, POLR3A, POLR1C, POLR2H, POLR3D, RPAP2, RPAP1, GPN1, RAE1,
Protein Size: 1133 -
分子量
- 128 kDa
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基因ID
- 55703
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NCBI登录号
- NM_018082, NP_060552
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UniProt
- Q9NW08
抗原
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