NSUN2 抗体 (C-Term)
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Quick Overview for NSUN2 抗体 (C-Term) (ABIN2783512)
抗原
See all NSUN2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- FINSRIITVS MEDVKILLTQ ENPFFRKLSS ETYSQAKDLA KGSIVLKYEP
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%
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产品特性
- This is a rabbit polyclonal antibody against NSUN2. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human NSUN2
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anti-NOP2/Sun Domain Family, Member 2 (NSUN2) (AA 508-767) antibody
NSUN2 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-NOP2/Sun Domain Family, Member 2 (NSUN2) (AA 432-509) antibodyNSUN2 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-NOP2/Sun Domain Family, Member 2 (NSUN2) (Internal Region) antibodyNSUN2 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-NOP2/Sun Domain Family, Member 2 (NSUN2) (AA 614-663) antibodyNSUN2 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, Pig, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-NOP2/Sun Domain Family, Member 2 (NSUN2) (C-Term) antibodyNSUN2 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-NOP2/Sun Domain Family, Member 2 (NSUN2) (AA 423-451) antibodyNSUN2 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB28701 unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 767 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "Stem cell function and stress response are controlled by protein synthesis." in: Nature, Vol. 534, Issue 7607, pp. 335-40, (2016) (PubMed).
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: "Stem cell function and stress response are controlled by protein synthesis." in: Nature, Vol. 534, Issue 7607, pp. 335-40, (2016) (PubMed).
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- NSUN2 (NOP2/Sun Domain Family, Member 2 (NSUN2))
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别名
- NSUN2
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背景
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Maturation of cytoplasmic tRNAs includes splicing of introns, which are located 1 nucleotide 3-prime from the anticodon in all intron-containing tRNA genes. In tRNA-leu(CAA), the first position of the anticodon, C34, is converted to 5-methylcytosine, a modification necessary to stabilize the anticodon-codon pairing and correctly translate the mRNA. NSUN2 is a methyltransferase that catalyzes the intron-dependent formation of 5-methylcytosine at C34 of tRNA-leu(CAA).Maturation of cytoplasmic tRNAs includes splicing of introns, which are located 1 nucleotide 3-prime from the anticodon in all intron-containing tRNA genes. In tRNA-leu(CAA), the first position of the anticodon, C34, is converted to 5-methylcytosine, a modification necessary to stabilize the anticodon-codon pairing and correctly translate the mRNA. NSUN2 encodes a methyltransferase that catalyzes the intron-dependent formation of 5-methylcytosine at C34 of tRNA-leu(CAA) (Brzezicha et al., 2006 [PubMed 17071714]).[supplied by OMIM].
Alias Symbols: FLJ20303, MISU, SAKI, TRM4
Protein Interaction Partner: SUMO2, SUMO3, UBC, SUMO1, NEDD8, TP53RK, PUS1, EFTUD1, XPO5, UGGT1, OSGEP, PANK4, THG1L, SH3GLB1, KIAA1279, UBXN7, TTLL12, ARPC2, ACTR2, ACTR3, FUBP1, TSN, SH3GL1, RPA1, RDX, RANGAP1, PPP2CB, PFDN5, PFDN1, NRD1, PPP1R12A, HARS, GTF2E1, CALU, CALR, UBD, VC
Protein Size: 767 -
分子量
- 86 kDa
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基因ID
- 54888
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NCBI登录号
- NM_017755, NP_060225
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UniProt
- Q08J23
抗原
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