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QPCT 抗体 (Middle Region)

QPCT 适用: 人, 小鼠, 大鼠, Cow, 绵羊, 犬, 马, 兔, 豚鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2783489
发货至: 中国
  • 抗原 See all QPCT 抗体
    QPCT (Glutaminyl-Peptide Cyclotransferase (QPCT))
    抗原表位
    • 7
    • 7
    • 7
    • 6
    • 4
    • 3
    • 1
    • 1
    Middle Region
    适用
    人, 小鼠, 大鼠, Cow, 绵羊, 犬, 马, 兔, 豚鼠
    宿主
    • 32
    • 7
    克隆类型
    • 35
    • 4
    多克隆
    标记
    • 17
    • 4
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This QPCT antibody is un-conjugated
    应用范围
    • 29
    • 23
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    序列
    SRHLAAKMAS TPHPPGARGT SQLHGMDLLV LLDLIGAPNP TFPNFFPNSA
    预测反应
    Cow: 86%, Dog: 79%, Guinea Pig: 93%, Horse: 79%, Human: 100%, Mouse: 79%, Rabbit: 93%, Rat: 100%, Sheep: 86%
    产品特性
    This is a rabbit polyclonal antibody against QPCT. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the middle region of human QPCT
    Top Product
    Discover our top product QPCT Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 361 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    QPCT (Glutaminyl-Peptide Cyclotransferase (QPCT))
    别名
    QPCT (QPCT 产品)
    别名
    GCT antibody, QC antibody, sQC antibody, QPCT antibody, 5730422A13Rik antibody, Qpctl1 antibody, RGD1562284 antibody, qpct antibody, glutaminyl-peptide cyclotransferase antibody, glutaminyl-peptide cyclotransferase (glutaminyl cyclase) antibody, glutaminyl-peptide cyclotransferase L homeolog antibody, QPCT antibody, Qpct antibody, M6_Spy0443 antibody, M5005_Spy_0416 antibody, M28_Spy0404 antibody, CJA_2408 antibody, CCNA_02733 antibody, Tsp_03182 antibody, qpct.L antibody
    背景
    QPCT is responsible for the biosynthesis of pyroglutamyl peptides. QPCT has a bias against acidic and tryptophan residues adjacent to the N-terminal glutaminyl residue and a lack of importance of chain length after the second residue. It also catalyzes N-terminal pyroglutamate formation. In vitro, catalyzes pyroglutamate formation of N-terminally truncated form of APP amyloid-beta peptides [Glu-3]-beta-amyloid. QPCT may be involved in the N-terminal pyroglutamate formation of several amyloid-related plaque-forming peptides.This gene encodes human pituitary glutaminyl cyclase, which is responsible for the presence of pyroglutamyl residues in many neuroendocrine peptides. The amino acid sequence of this enzyme is 86 % identical to that of bovine glutaminyl cyclase. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: GCT, QC, sQC
    Protein Interaction Partner: CAND1, DCUN1D1, COPS5, CUL1, CUL2, CUL3, CUL4A, CUL4B, CUL5, NEDD8, UBC,
    Protein Size: 361
    分子量
    38 kDa
    基因ID
    25797
    NCBI登录号
    NM_012413, NP_036545
    UniProt
    Q16769
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