QPCT 抗体 (Middle Region)
Quick Overview for QPCT 抗体 (Middle Region) (ABIN2783489)
抗原
See all QPCT 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- SRHLAAKMAS TPHPPGARGT SQLHGMDLLV LLDLIGAPNP TFPNFFPNSA
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预测反应
- Cow: 86%, Dog: 79%, Guinea Pig: 93%, Horse: 79%, Human: 100%, Mouse: 79%, Rabbit: 93%, Rat: 100%, Sheep: 86%
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产品特性
- This is a rabbit polyclonal antibody against QPCT. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human QPCT
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anti-Glutaminyl-Peptide Cyclotransferase (QPCT) (AA 1-361) antibody
QPCT 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Glutaminyl-Peptide Cyclotransferase (QPCT) (AA 1-361) antibodyQPCT 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Glutaminyl-Peptide Cyclotransferase (QPCT) (AA 29-361) antibodyQPCT 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Glutaminyl-Peptide Cyclotransferase (QPCT) (AA 29-361) antibodyQPCT 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Glutaminyl-Peptide Cyclotransferase (QPCT) (AA 262-359) antibodyQPCT 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Glutaminyl-Peptide Cyclotransferase (QPCT) (AA 262-359) antibodyQPCT 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4E11 unconjugated
anti-Glutaminyl-Peptide Cyclotransferase (QPCT) (AA 262-359) antibodyQPCT 适用: 人 ELISA, IHC (p) 宿主: 小鼠 Monoclonal 3G2 unconjugated
anti-Glutaminyl-Peptide Cyclotransferase (QPCT) (AA 1-361) antibodyQPCT 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Glutaminyl-Peptide Cyclotransferase (QPCT) (AA 216-265) antibodyQPCT 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, 绵羊, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 361 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- QPCT (Glutaminyl-Peptide Cyclotransferase (QPCT))
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别名
- QPCT
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背景
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QPCT is responsible for the biosynthesis of pyroglutamyl peptides. QPCT has a bias against acidic and tryptophan residues adjacent to the N-terminal glutaminyl residue and a lack of importance of chain length after the second residue. It also catalyzes N-terminal pyroglutamate formation. In vitro, catalyzes pyroglutamate formation of N-terminally truncated form of APP amyloid-beta peptides [Glu-3]-beta-amyloid. QPCT may be involved in the N-terminal pyroglutamate formation of several amyloid-related plaque-forming peptides.This gene encodes human pituitary glutaminyl cyclase, which is responsible for the presence of pyroglutamyl residues in many neuroendocrine peptides. The amino acid sequence of this enzyme is 86 % identical to that of bovine glutaminyl cyclase. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: GCT, QC, sQC
Protein Interaction Partner: CAND1, DCUN1D1, COPS5, CUL1, CUL2, CUL3, CUL4A, CUL4B, CUL5, NEDD8, UBC,
Protein Size: 361 -
分子量
- 38 kDa
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基因ID
- 25797
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NCBI登录号
- NM_012413, NP_036545
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UniProt
- Q16769
抗原
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