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QPCT 抗体 (Middle Region)

The 兔 多克隆 anti-QPCT antibody is suitable to detect QPCT in samples from 人, 小鼠, 大鼠, Cow, 犬, 马, 绵羊, 豚鼠 和 兔. It has been validated for WB.
产品编号 ABIN2783489
发货至: 中国
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Quick Overview for QPCT 抗体 (Middle Region) (ABIN2783489)

抗原

See all QPCT 抗体
QPCT (Glutaminyl-Peptide Cyclotransferase (QPCT))

适用

人, 小鼠, 大鼠, Cow, 犬, 马, 绵羊, 豚鼠, 兔

宿主

  • 28
  • 9

克隆类型

  • 31
  • 6
多克隆

标记

  • 20
  • 3
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This QPCT antibody is un-conjugated

应用范围

  • 26
  • 18
  • 6
  • 5
  • 3
  • 2
  • 1
  • 1
Western Blotting (WB)
  • 抗原表位

    • 8
    • 7
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    Middle Region

    序列

    SRHLAAKMAS TPHPPGARGT SQLHGMDLLV LLDLIGAPNP TFPNFFPNSA

    预测反应

    Cow: 86%, Dog: 79%, Guinea Pig: 93%, Horse: 79%, Human: 100%, Mouse: 79%, Rabbit: 93%, Rat: 100%, Sheep: 86%

    产品特性

    This is a rabbit polyclonal antibody against QPCT. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the middle region of human QPCT
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 361 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    QPCT (Glutaminyl-Peptide Cyclotransferase (QPCT))

    别名

    QPCT

    背景

    QPCT is responsible for the biosynthesis of pyroglutamyl peptides. QPCT has a bias against acidic and tryptophan residues adjacent to the N-terminal glutaminyl residue and a lack of importance of chain length after the second residue. It also catalyzes N-terminal pyroglutamate formation. In vitro, catalyzes pyroglutamate formation of N-terminally truncated form of APP amyloid-beta peptides [Glu-3]-beta-amyloid. QPCT may be involved in the N-terminal pyroglutamate formation of several amyloid-related plaque-forming peptides.This gene encodes human pituitary glutaminyl cyclase, which is responsible for the presence of pyroglutamyl residues in many neuroendocrine peptides. The amino acid sequence of this enzyme is 86 % identical to that of bovine glutaminyl cyclase. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: GCT, QC, sQC
    Protein Interaction Partner: CAND1, DCUN1D1, COPS5, CUL1, CUL2, CUL3, CUL4A, CUL4B, CUL5, NEDD8, UBC,
    Protein Size: 361

    分子量

    38 kDa

    基因ID

    25797

    NCBI登录号

    NM_012413, NP_036545

    UniProt

    Q16769
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