SULT1E1 抗体 (Middle Region)
Quick Overview for SULT1E1 抗体 (Middle Region) (ABIN2783458)
抗原
See all SULT1E1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- LMVAGHPNPG SFPEFVEKFM QGQVPYGSWY KHVKSWWEKG KSPRVLFLFY
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预测反应
- Dog: 85%, Guinea Pig: 92%, Horse: 86%, Human: 100%, Mouse: 83%, Rabbit: 92%, Rat: 83%
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产品特性
- This is a rabbit polyclonal antibody against SULT1E1. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human SULT1E1
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 294 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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Bisphenol A sulfonation is impaired in metabolic and liver disease." in: Toxicology and applied pharmacology, Vol. 292, pp. 75-84, (2016) (PubMed).
: "Downregulation of sulfotransferase expression and activity in diseased human livers." in: Drug metabolism and disposition: the biological fate of chemicals, Vol. 41, Issue 9, pp. 1642-50, (2013) (PubMed).
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Bisphenol A sulfonation is impaired in metabolic and liver disease." in: Toxicology and applied pharmacology, Vol. 292, pp. 75-84, (2016) (PubMed).
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- SULT1E1 (Sulfotransferase Family 1E Member 1 (SULT1E1))
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别名
- SULT1E1
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背景
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Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic compounds. These cytosolic enzymes are different in their tissue distributions and substrate specificities. The gene structure (number and length of exons) is similar among family members. This gene encodes a protein that transfers a sulfo moiety to and from estrone, which may control levels of estrogen receptors.
Alias Symbols: EST, EST-1, MGC34459, STE, ST1E1
Protein Interaction Partner: PDE9A, LRIF1, COPS6, RBM48, IGSF21, ENOX1, SETDB1, C14orf1, SULT2B1, UNC119, BMPR2, TP53, EEF1A1,
Protein Size: 294 -
分子量
- 35 kDa
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基因ID
- 6783
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NCBI登录号
- NM_005420, NP_005411
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UniProt
- P49888
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途径
- Steroid Hormone Biosynthesis
抗原
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