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SPTLC2 抗体 (N-Term)

This 兔 多克隆 antibody specifically detects SPTLC2 in WB. It exhibits reactivity toward 人, 小鼠, 大鼠, Cow, 豚鼠, 兔, 斑马鱼, 犬 和 马.
产品编号 ABIN2783451
发货至: 中国
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Quick Overview for SPTLC2 抗体 (N-Term) (ABIN2783451)

抗原

See all SPTLC2 抗体
SPTLC2 (serine Palmitoyltransferase, Long Chain Base Subunit 2 (SPTLC2))

适用

  • 52
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  • 1
人, 小鼠, 大鼠, Cow, 豚鼠, 兔, 斑马鱼, 犬, 马

宿主

  • 53
  • 1
兔

克隆类型

  • 54
多克隆

标记

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  • 1
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  • 1
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This SPTLC2 antibody is un-conjugated

应用范围

  • 49
  • 22
  • 19
  • 7
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  • 1
Western Blotting (WB)
  • 抗原表位

    • 7
    • 6
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    • 1
    • 1
    • 1
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    N-Term

    原理

    SPTLC2 Antibody - N-terminal region

    序列

    VLTYVGYGVL TLFGYLRDFL RYWRIEKCHH ATEREEQKDF VSLYQDFENF

    预测反应

    Cow: 100%, Dog: 91%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

    产品特性

    This is a rabbit polyclonal antibody against SPTLC2. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N terminal region of human SPTLC2
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    说明

    We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP48652-100UG

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.5 mg/mL

    缓冲液

    Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    prevent freeze-thaw cycles

    储存条件

    4 °C,-20 °C

    储存方法

    For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    SPTLC2 (serine Palmitoyltransferase, Long Chain Base Subunit 2 (SPTLC2))

    别名

    SPTLC2

    背景

    Background Information: SPTLC2 is a long chain base subunit of serine palmitoyltransferase. Serine palmitoyltransferase, which consists of two different subunits, is the key enzyme in sphingolipid biosynthesis. It catalyzes the pyridoxal-5-prime-phosphate-dependent condensation of L-serine and palmitoyl-CoA to 3-oxosphinganine. Mutations in this gene were identified in patients with hereditary sensory neuropathy type I.This gene encodes a long chain base subunit of serine palmitoyltransferase. Serine palmitoyltransferase, which consists of two different subunits, is the key enzyme in sphingolipid biosynthesis. It catalyzes the pyridoxal-5-prime-phosphate-dependent condensation of L-serine and palmitoyl-CoA to 3-oxosphinganine. Mutations in this gene were identified in patients with hereditary sensory neuropathy type I. Alternatively spliced variants encoding different isoforms have been identified. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-973 AB011098.1 1-973 974-1108 BQ338973.1 306-440 1109-3679 AB011098.1 1109-3679 3680-4578 AB011098.1 3682-4580 4579-4876 BG024616.1 326-623 4877-6812 AB011098.1 4879-6814 6813-7189 W24363.1 55-431 7190-7250 BM992457.1 1-61 c

    Gene Name: Serine palmitoyltransferase, long chain base subunit 2

    Alternative Symbols: LCB2, SPT2, HSN1C, LCB2A, NSAN1C, hLCB2a

    Protein Name: Serine palmitoyltransferase 2

    分子量

    63kDa

    基因ID

    9517

    NCBI登录号

    NP_004854

    UniProt

    O15270
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