MAP4K2 抗体 (N-Term)
Quick Overview for MAP4K2 抗体 (N-Term) (ABIN2783443)
抗原
See all MAP4K2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- HLHPMRALML MSKSSFQPPK LRDKTRWTQN FHHFLKLALT KNPKKRPTAE
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预测反应
- Cow: 100%, Dog: 93%, Guinea Pig: 85%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 93%, Rabbit: 85%, Rat: 100%, Zebrafish: 92%
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产品特性
- This is a rabbit polyclonal antibody against MAP4K2. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human MAP4K2
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 820 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- MAP4K2 (Mitogen-Activated Protein Kinase Kinase Kinase Kinase 2 (MAP4K2))
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别名
- MAP4K2
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背景
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MAP4K2 is a member of the serine/threonine protein kinase family. Although this kinase is found in many tissues, its expression in lymphoid follicles is restricted to the cells of germinal centre, where it may participate in B-cell differentiation. This kinase can be activated by TNF-alpha, and has been shown to specifically activate MAP kinases. This kinase is also found to interact with TNF receptor-associated factor 2 (TRAF2), which is involved in the activation of MAP3K1/MEKK1.The protein encoded by this gene is a member of the serine/threonine protein kinase family. Although this kinase is found in many tissues, its expression in lymphoid follicles is restricted to the cells of germinal centre, where it may participate in B-cell differentiation. This kinase can be activated by TNF-alpha, and has been shown to specifically activate MAP kinases. This kinase is also found to interact with TNF receptor-associated factor 2 (TRAF2), which is involved in the activation of MAP3K1/MEKK1.
Alias Symbols: BL44, GCK, RAB8IP
Protein Interaction Partner: HSP90AA1, UBC, MAP3K11, MAP3K1, POT1, MCM3AP-AS1, NACAD, SNRNP35, PRDX4, SERPINA4, HNRNPA2B1, XRCC6, DEFB1, TRAF2, RAB8A, MAP2K4,
Protein Size: 820 -
分子量
- 91 kDa
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基因ID
- 5871
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NCBI登录号
- NM_004579, NP_004570
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UniProt
- Q12851
抗原
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